Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"emboli"”.
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Lipid Micro Emboli in Cardiac Surgery
… It includes the characterization of lipid micro emboli in shed mediastinal blood during cardiac surgery. The reuse of blood directly by cardiotomy suction is a common practice in order to reduce the need of blood transfusions. In shed mediastinal blood we showed that there is an abundance of …
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Generating Gaseous Emboli Mimics in an ECMO Flow Phantom
… (ECMO) therapy are prone to developing emboli. These unattached masses of solid blood clots and gaseous air bubbles have the potential to occlude blood vessels and lead to complications such as neurological damage. Existing ultrasound methods for detecting and characterizing them are …
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Best Practices in The Use of Vena Cava Filters oo Prevent Pulmonary Emboli in Trauma Patients
… a deep vein thrombosis and subsequent pulmonary embolism can have catastrophic implications including death. There are unique characteristics and injury patterns in trauma patients that may make chemoprophylaxis for deep vein thrombosis contraindicated. These include traumatic brain injury, …
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A retrospective review of CTPA confirmed pulmonary emboli in COVID-19 patients admitted to Groote Schuur Hospital, Cape Town
Background: A high incidence of thromboembolic phenomena has been widely reported in patients with COVID-19 pneumonia. There is, however, a paucity of data detailing the incidence and characteristics of pulmonary emboli (PE) in COVID-19 patients in the South African setting. An improved …
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The Safety and Cost-Effectiveness of Carotid Angioplasty and Stenting in Calgary
… Procedural monitoring showed a median of 224.5 emboli. Large emboli correlated with MRI lesions after adjusting for age and symptoms status. Conclusion To improve the outcomes of carotid stenting, research should aim to improve the procedure safety without increasing its costs.
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Aspects of retransfusion of shed blood in cardiac surgery
… response, hemolysis and coagulopathy. Emboli of various matters has also been studied. Whether they affect the function of various organs is an ongoing debate. Renal dysfunction after cardiac surgery is a well known complication. Monitoring of renal function is important, both for the …
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Quantitative analysis and modeling of microembolic phenomena
… that govern microvascular occlusion secondary to embolic phenomenon. Bulk and individual properties of microembolic particles were characterized using light microscopy, SEM and optically-based particle analysis. Particulate probability distributions were created from imaging data using Matlab. …
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Role of shNDPK and E-Cadherin in Growth and Metastasis of an Inflammatory Breast Cancer Model (MARY-X)
… exhibits the formation of florid lymphovascular emboli in vivo and spheroid formation in vitro. IBC is highly invasive and metastatic and our model presents the same in mice as it does in human. Therefore, studying the molecular processes involved in this IBC murine model will allow us to uncover …
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When working towards an optimised Carotid stenting procedure does patient, procedural and pharmacological selection impact on outcome.
… on outcomes. Using transcranial Doppler detected embolic events as a clinical endpoint for comparison with the clopidogrel dependant pathways of platelet activation the study hoped to show a direct effect of the degree of platelet inhibition on the number of emboli detected. This was not shown to …
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In Vitro and In Silico Study of Deposition on Textured Biomaterials: Towards Biofunctionalization of Ventricular Cannula
… device (LVAD) is the inflow cannula, where emboli are produced. The emboli may be later ingested and ejected from the pump. A widely explored strategy to prevent surface-induced thrombosis in cardiovascular implants is to promote stable endothelium, which is the natural thrombo-resistant …
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Apoptotic cells promote circulating tumor cell survival and metastasis
… metastasis by establishing CTC-supportive emboli, and suggests points of intervention that may reduce the pro-metastatic effect of apoptotic cells.
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High performance lattice boltzmann method yield-stress calculations based on intravital images of clot formation in live mice
Thrombo-embolic infarction is the major cause of mortality and morbidity in the United States, causing over 1 million strokes, heart attacks and other life-threatening thrombotic events each year in the United States. Conversely, deficiencies in these processes result in severe bleeding risks. The …
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"A syndrome so characteristic" Molecular and clinical studies of Fusobacterium necrophorum and Lemierre's syndrome
… vein thrombophlebitis and septic pulmonary emboli. The first studies underlying this thesis focused on bacterial interaction with coagulation. The contact system initiates the intrinsic pathway of coagulation and the release of the pro-inflammatory peptide bradykinin. We found that the …
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Pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension in Cape Town, South Africa
… potentially curative therapy for chronic thromboembolic pulmonary hypertension (CTEPH), associated with impressive improvements in symptoms and haemodynamics. However, it is only offered at a few centres in South Africa. The characteristics and outcomes of patients undergoing PEA in Cape Town …
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Comparison of patient outcome for aortic valve replacement verses transcatheter aortic valve replacement
… After concluding that the strokes were due to emboli released during mechanical movement during surgery, new technologies have begun to be developed to combat the stroke risk. One device that is used is a deflection device that ensures that an embolus does not have access to cerebral …
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Ultrasound-based Noninvasive Monitoring Methods for Neurocritical Care
… flow measurement and for embolus detection and embolic load quantification. The blood flow waveform measurements were also used to determine intracranial pressure (ICP), intracranial compliance (ICC), and cerebrovascular resistance (CVR) in a model-based, noninvasive, patient-specific, and …
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Inflammatory Breast Cancer: The Immune Perspective
… of the characteristic tightly packed tumor emboli seen in IBC samples.</p> <p>This data offers insight into the unique pathology of IBC by suggesting that tumor immune interactions in the tumor microenvironment contribute to the aggressive nature of IBC implying that immune induced …
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A Study to Demonstrate the Immediate Destination of an Embolus Formed in the Lumen of a Peripheral Venous Catheter
… and (4) probable relationship of multiple small emboli from catheter irrigation to fatal embolization.</p> <p>The experimental method of research was used to collect data on twenty-two rabbits. Each rabbit was injected with a clot tagged with <sup>131</sup> I-MAA in the foreleg and later scanned …
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Risk-Factor Induced Changes In The Breast Microenvironment Facilitate Inflammatory Breast Cancer Progression and Lymphovascular Invasion
… is characterized by florid lymphovascular tumor emboli clogging dermal lymphatics. This leads to “classic” symptoms of breast swelling and skin edema or discoloration. To date, unique genomic drivers which differentiate IBC from non-IBC invasive breast cancers have not been identified …
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Retrospective review of the incidence of venous thromboembolism in pregnancy and the puerperium and identification of presenting complaints of pregnancy-related venous thromboembolism at Groote Schuur Maternity Centre, Cape Town between 1 January 2016 and 31 December 2016
Background: Venous thromboembolism is one of the leading causes of morbidity and mortality around the world. In addition to the immediate morbidity, there is significant implications on delivery plans, future options of contraception and thromboprophylaxis in subsequent pregnancies. At present, no …