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Showing 1 to 12 of 12 for “"electrospun scaffold"”.
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Effect of Electrospun Mesh Diameter, Mesh Alignment, and Mechanical Stretch on Bone Marrow Stromal Cells for Ligament Tissue Engineering
… seeding bone marrow stromal cells (BMSCs) onto electrospun scaffolds, processing them into cords that allow cell infiltration, and conditioning them with uniaxial cyclic stretch. These steps were addressed in three complimentary studies to establish new methods to engineer a tissue with …
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Design and nondestructive imaging of a bioengineered vascular graft endothelium
… that consist of a combination of vascular scaffolds and cells. A major challenge in creating a functional bioengineered vascular graft is development of a confluent endothelium on the lumen that is able to resist detachment under physiologic fluid flow. In addition, methodologies used to …
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STUDIES OF CELL MOTILITY AND DIFFERENTIATION IN COMPLEX 3D IN VITRO MICROENVIRONMENT
… </p> <p>In this work, 3D dynamic shape memory scaffolds were developed and employed to investigate cell motility and differentiation behaviors when the cellular microenvironment dynamically changes in vitro. The scaffolds have fibrous structure, which can potentially mimic the collagen matrix …
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Siam weed based hydrogel hybrid for tissue engineering
… technique to produce Siam weed-gelatin electrospun scaffold as a successful 3D skin tissue engineering grafts. The effects of content of Siam weed extracts on the electrospun scaffolds are determined using scanning electron microscopy, Fourier Transfom Infrared spectroscopy and …
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A Novel Drug Delivery System Incorporates a Functional Composite Scaffold Derived from Taxifolin with Potential Cytotoxic and Anticancer Effects on Triple Negative Breast Cancer
… of a novel taxifolin delivery system via electrospun PCL scaffolds to enhance anticancer and therapeutic efficacy of the drug post-operatively. The Comet assay was utilised to analyse DNA damage and repair in lymphocytes from breast cancer patients versus healthy controls. CCK-8, qPCR and …
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A Novel Drug Delivery System Incorporates a Functional Composite Scaffold Derived from Taxifolin with Potential Cytotoxic and Anticancer Effects on Triple Negative Breast Cancer
… of a novel taxifolin delivery system via electrospun PCL scaffolds to enhance anticancer and therapeutic efficacy of the drug post-operatively. The Comet assay was utilised to analyse DNA damage and repair in lymphocytes from breast cancer patients versus healthy controls. CCK-8, qPCR and …
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Novel Apparatus to Control Electrospinning Fiber Orientation for the Production of Tissue Engineering Scaffolds
… the three-dimensional architecture of an electrospun scaffold to further improve its utility in tissue engineering. The efficacy of using this technique has been well documented and can be adapted to produce tissue engineering scaffolds for a variety of tissues and organs. This apparatus …
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Tissue Engineering Cartilage with a Composite Electrospun and Hydrogel Scaffold
… and/or molecular signals. Biodegradable scaffolds serve as a temporary replacement for the tissue until it has regenerated. Two types of scaffolds that have been used in tissue engineering are electrospun scaffolds and hydrogels. We have proposed and fabricated a scaffold for cartilage …
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Complementary strategies to promote the regeneration of bone-ligament transitions using graded electrospun scaffolds
… to graft failure. In contrast, tissue-engineered scaffolds possessing gradients in properties can potentially guide the establishment of phenotypic gradients in bone marrow stromal cells (BMSCs), and thus aid the regeneration of B-L transitions in the long-term. Towards the eventual goal of …
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Development and Characterization of Tunable, Bioinspired Electrospun Constructs for Skeletal Muscle Engineering
… of skeletal muscle, the natural polymer was electrospun with varying degrees of fiber alignment and varying degrees of crosslinking. The impact of scaffold architecture and crosslinking density on fiber swelling, degradation kinetics, and mechanical properties was then evaluated. After …
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Creation and Characterization of Several Polymer/Conductive Element Composite Scaffolds for Skeletal Muscle Tissue Engineering
… factors. Electrospinning produces a non-woven scaffold out of biomaterials with fiber diameters ranging from nanometers to microns to create an extracellular-like matrix on which cells attach and proliferate. Our focus is on synthetic polymers, specifically poly(D,L-lactide) (PDLA), …
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Synergistic combination of stem cell-based approach and automated controlled dynamic culture for advanced dental tissue engineering
L'abstract è presente nell'allegato / the abstract is in the attachment