Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"electroretinography"”.
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Development of Multielectrode Electroretinography (meERG) for Human Clinical Use
Development of Multielectrode Electroretinography (meERG) for Human Clinical use. Introduction Progressive retinal diseases such as macular degeneration, glaucoma, and retinitis pigmentosa begin with localized dysfunction that spreads, often remaining undetected until advanced stages. Existing …
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The Isolation of Human Rod and Cone Photoreceptor Activity combining Electroretinography and Silent Substitution Techniques
Aims: The electroretinogram (ERG) can be used to independently assess the function of rod and cone photoreceptors within the human retina. The work in this thesis sought to investigate an alternative method of recording the ERG, using the silent substitution paradigm (Estevez and Spekreijse 1982). …
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Clinical aspects of the electrical response of the human eye to an intense light stimulus
… from a standard clinical procudure known as electroretinography The method to be described enables one to observe the response in more detail than has been hitherto possible Two recently discovered components of the electroretinogram are clearly shown using this technique. One of these …
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Toward accessible evaluation of the electrophysiology of human vision
… But beyond the clinical implications, accessible electroretinography presents an unprecedented opportunity for individuals to characterize their specific experience of color, contrast, and movement, making way for a whole new paradigm of tailored display technologies.
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Multifokale Elektroretinographie bei retinalen Gefäßverschlüssen
… lead to characteristical changes in multifocal electroretinography. Future studies have to show if this technique can give prognostic information about neovascularisation risks. The intraindividual comparison of affected and fellow eye promises to be more sensitive than comparison with a normal …
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Controlled ablation of rod photoreceptors in transgenic Xenopus laevis
… two days after drug exposure. We adapted an electroretinography apparatus, and protocols designed for mammals to measure functional changes in X. laevis rod and cone derived responses. We observed delayed secondary cone cell dysfunction after induced rod cell apoptosis, which was subsequently …
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Normalwerterhebung bei der multifokalen Elektroretinographie bei Monitor- und SLO-Stimulation
… and analyse reference values in multifocal electroretinography for the University Eye Clinic of Aachen. 61 healthy subjects (age 50,0 ± 20,0) were examined with monitor stimulation and 15 healthy subjects (43,4 ± 20,0) with SLO-stimulation. Mean values and standard deviations were calculated …
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Effect of Drugs on Rabbit Retina
… have been investigated in the rabbit eye, using electroretinography, ocular examination and histochemical methods. Rifabutin is a broad spectrum antibiotic with known ocular adverse effects (corneal opacities, uveitis and vascular retinopathy) in the human eye. In the rabbit eye rifabutin causes …
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Effects of connexin modulators in animal models of retinal degeneration: delivery and treatment efficacy
… the efficacy of the treatment long term. Using electroretinography, optical coherence tomography imaging and molecular approaches investigation was performed to further understand the potential of these novel connexin based treatments in the treatment of early signs of the disease. The study of …
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X-LINKED RETINOSCHISIS ELECTROPHYSIOLOGY, MOLECULAR GENETICS AND TREATMENT
… retinoschisin distribution in WT retina. The electroretinography recordings showed reversal of the electronegative waveform and restoration of the normal positive b-wave. In paper II, we treated the mice at an earlier time point, 14 days, and followed them out to 14 months. We demonstrated …
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The role of Interleukin-33 in retinal degenerative diseases
… infiltration was exhibited for at least 28 days. Electroretinography (ERG) revealed lower a- and b-wave amplitudes at day 28 post-RD in IL-33KO mice compared to WT RD mice. The numbers of cone photoreceptor cells and their synapses were significantly lower in the retina of IL-33KO mice subjected …
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Comparing Differentiated Rod And Cone Transcriptomes Reveals Rax As A Controller Of A Defined Cone Gene Regulatory Program
… with RAX, by a second round of RNA-seq. Electroretinography (ERG) was used to correlate RAX-specific GRN with retina function. <br></br><br></br> <b>Results</b><br></br> Histological analysis showed unambiguous expression of both mCherry and eGFP in rods, whereas cones showed exclusive …
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Experimental porcine models of retinal ischemia
Retinal ischaemia resulting from e.g. diabetes, vein thrombosis or arterial occlusion, is one of the major causes of visual impairment and blindness. Although new methods of treatment are being developed, there is still a need for more effective pharmacological forms of treatment. The aim of this …
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Retinal function in deaf-blind syndromes
A variety of disorders can cause retinal degeneration and hearing impairment, and it is of great value to have an early diagnosis since there is a large variation in phenotype and prognosis both within and between the different disorders. The general aim of this thesis was to characterize the …
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Problematika lokálních a celkových vedlejších účinků cytostatik při jejich experimentálním intraokulárním a periokulárním podání
Úvod: Standardizovaná lécba intravenózne aplikovanou chemoterapií nepostacuje k dosažení kontroly nad volne plovoucími retinoblastomovými partikulemi ve sklivci u pokrocilého stupne C, D a E retinoblastomu. Periokulární a intravitreální injekce chemoterapeutik je slibnou cestou k dosažení maximální …