Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"electron transport system"”.
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Hibernation is super complex: dynamics of electron transport system supercomplexes
The electron transport system complexes form supercomplexes (SCs) within mitochondrial membranes, perhaps increasing respiratory capacity or reducing reactive oxygen species production. My project aimed to determine the abundance, composition, and stability of SCs in a hibernator. Hibernators have …
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Pyruvate Oxidase and the Cytochrome D Terminal Oxidase of Escherichia Coli
… components of the Escherichia coli aerobic electron transport system were studied, pyruvate oxidase and the cytochrome d terminal oxidase. Three general subjects were treated: (i) the active site structure and catalytic mechanism of pyruvate oxidase, (ii) the role of pyruvate oxidase in the …
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The role of the cytochrome B and cytochrome C oxidase III genes in the immune response of the South African abalone, Haliotis midae
… In order to establish better health management systems, and to implement alternative therapies such as probiotics, a better understanding of how the abalone immune system functions, and specifically how it responds to stimulation, is necessary. Two genes of the electron transport system, …
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Electron beam dynamics for the ISIS bremsstrahlung beam generation system
An electron beam transport system was designed for use in the Bremsstrahlung Beam Generation System of the Integrated Stand-off Inspection System (ISIS). The purpose of this electron transport system was to provide for electron beam diagnostics and energy selection while also positioning the …
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Hydrogenase utilization and regulation in species of methanosarcina
… a substrate, while the others can use H2 as an electron carrier via a hydrogen cycling mechanism, which was previously demonstrated for Methanosarcina barkeri. Both uses of H2 require the activity of three different hydrogenase enzymes, however, M. barkeri can also utilize an electron transport …
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Temperature-dependent alterations of brown adipose tissue metabolism during hibernation in the thirteen-lined ground squirrel, <i>Ictidomys tridecemlineatus</i>.
… IBE. Contrary to these results, activities of electron transport system enzymes and brown adipocyte respiration did not differ between torpor and IBE, regardless of assay temperature. The data suggest that BAT mitochondria become less temperature sensitive during torpor, allowing sustained …
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The Mechanism of Aerotaxis in SALMONELLA TYPHIMURIUM
… are unsuitable for analyzing the role of the electron transport system in aerotaxis. In this study the biochemical mechanism of aerotaxis and its relationship to other chemotaxis pathways in <em>Salmonella typhimurium</em> was explored with the aid of two new assays which imposed an oxygen …
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The effect of hybridization on metabolism and hypoxia tolerance in sunfish
… F1 hybrids (male bluegill x female pumpkinseed). Electron transport system (ETS) complex activities were examined in isolated mitochondria of bluegill, pumpkinseed and hybrids. The specific activities (units per mg mitochondrial protein) of complexes I, II, and V were indistinguishable between …
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The selective advantage of mitochondrial DNA: Mitotype by diet interactions influence organismal fitness and longevity
… to the mitochondria at different stages of the electron transport system to produce cellular energy. Thus modulating diet and other environmental factors may elucidate favourable mutations as these mutations may be context dependent, being favourable in one context, but deleterious in another. …
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Targeting neurodegenerative phenotypes and mitochondrial dysfunction in a Drosophila Melanogaster model of Parkinson’s Disease
… particularly involving Complex I of the electron transport system and mitophagy pathways, is significantly affected in the pathogenesis of PD. This study investigates the roles of NUBPL and PINK1 mutations in mitochondrial dysfunction, focusing on ageing as a risk factor, using Drosophila …
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Oxygen Sensing by the Aer and Tsr Receptors of Escherichia Coli
… se but, sense the internal energy state via the electron transport system (ETS) in a previously unidentified mechanism. Proton motive force (PMF) and electron flow were proposed as possible sensory signals but, distinguishing between the two was not possible, previously, in live, motile cells. I …
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Metabolic downregulation during diapause in embryos of Artemia franciscana
… are added simultaneously, the increased electron flow through the electron transport system allows the detection of respiratory inhibition by the phosphorylation system (i.e., the F<sub>1</sub>.F<sub>o</sub>-ATP synthase, adenine nucleotide transporter, and phosphate transporter). This …
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Identification and Characterization of Aer, an Energy Sensor in Escherichia Coli
… used to identify the upstream component in the electron transport system that signals to Aer. The yeast two hybrid system was utilized to assay interactions between Aer and all other proteins encoded by a <em>E.coli</em> genomic library. The role of NADH dehydrogenase I in aerotaxis was also …
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Novel approaches to treat mitochondrial complex-I mediated defects in disease
… within complex I (CI) of the mitochondrial electron transport system has been implicated in a number of disease states ranging from cardiovascular diseases to neuro-ophthalmic indications. Herein, we provide three novel approaches to model and study the impacts of injury on the function of …
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The effect of beta-oxidation or TCA cycle inhibition on mitochondrial function and the sensitivity of high resolution respiratory detection
… within each individual pathway, transfer of electrons through the electron transport system (ETS) and oxidative phosphorylation for ATP generation) may be a more effective assessment technique. High resolution respirometry (HRR) is a recently developed technique that accounts for substrate …