Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"electrical remodeling"”.
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Ankyrin-B and Mtor Complex 1 In The Regulation of Electrical Activities In The Heart
… activity is paramount in the regulation of electrical activities in the brain and the heart. In the brain, the tumor suppressor gene <em>TSC2</em> encodes the protein product tuberin that interacts with hamartin to form a heterodimer Tuberous Sclerosis Complex (TSC) that regulates mTORC1. …
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Mechanically-induced intercellular remodeling of cardiomyocytes by magnetic micromanipulation
… gap junctions are responsible for maintaining electrical impulse propagation. Connexin43 (Cx43) is the most abundant gap junction in the heart, and studies have shown that spatial heterogeneity of Cx43 may promote electrical instability and anisotropic conduction pathways that may cause cardiac …
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Electrocardiographic Consequences Of Electrical And Anatomical Remodeling In Diabetic And Obese Humans
… and obesity on BSPs, we hope to reveal the electrical phenotype of diabetes in body-surface ECGs in the presence of obesity. Methods. A Bidomain Platform was constructed to link heart-surface transmembrane potentials: TMPs) and BSPs. The Forward-Problem Module of the platform calculates BSPs …
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Calcium Remodeling through Different Signaling Pathways in Heart Failure: Arrhythmogenesis Studies of Pyk2, Dystrophin, and β-adrenergic Receptor Signaling
… and concomitant structural and functional remodeling, especially Ca handling. Ca is critical in both the electrical and mechanical properties of cardiac myoctyes, and much is known about ionic currents and the normal excitation-contraction coupling process. In heart failure, distinct …
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Molecular Dissection of IA Channels in Cortical Pyramidal Neurons
… encoding components of I <sub>A</sub> results in electrical remodeling that is Kv α-subunit specific. Accumulating, evidence indicates that native neuronal Kv4 channels function in macromolecular protein complexes that contain accessory subunits and other regulatory molecules. The …
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RUOLO DELLA STIMOLAZIONE VAGALE SULLA PROLIFERAZIONE DEI FIBROBLASTI CARDIACI IN VIVO IN MODELLO ANIMALE DI FIBRILLAZIONE ATRIALE.
… Recent studies have demonstrated that structural remodeling, involving prominent fibrotic changes, is a fundamental determinant of the perpetuation of AF, and contributes synergistically with electrical remodeling to the AF substrate. Atrial fibrosis is a hallmark feature of arrhythmogenic …
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Cardiac PI3Kα Signaling and K+ Channel Regulation in Cardiac Hypertrophy and Heart Failure
… hypertrophy" is not associated with electrical abnormalities or increased arrhythmia risk, suggesting that repolarizing K<super>+</super> currents are upregulated, in parallel with the increase in myocyte size, to maintain normal cardiac function. To explore this hypothesis directly, …
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Global sequence and dispersion of ventricular repolarization: In vivo validation of non-invasive parameters using monophasic action potential mapping technique
… happen within a few hours in vivo, implying that electrical remodeling of the ventricles may be rapidly induced by altered activation sequence. In addition, the global dispersion of EOR times during LVEpi pacing was significantly greater than those during RA and RVEndo pacing, whereas no …
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Die Entwicklung des myokardialen Hypertrophiebildes im Magnetokardiogramm und die Veränderungen unter dem AT1-Antagonisten Losartan in einem transgenen Rattenmodell
… Arbeit war es, Aussagen über das elektrische Remodeling der myokardialen Hypertrophieentwicklung an doppeltransgenen Ratten (Überexpression von humanen Renin und Angiotensinogen) mit Hilfe der Magnetokardiographie (MKG) zu treffen, und die Veränderung unter Losartantherapie zu detektieren. Das …