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Showing 1 to 20 of 81 for “"eicosapentaenoic acid"”.
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Development of an eicosapentaenoic acid production bioprocess using an indigenous microalgal isolate
Eicosapentaenoic acid (EPA; 20:5) is an omega-3 polyunsaturated fatty acid of increasing interest as a nutraceutical. An indigenous microalgal isolate suitable for an EPA bioprocess was selected by screening monoalgal isolates from the Council for Scientific and Industrial Research (CSIR) …
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Production of Eicosapentaenoic acid from biodiesel derived crude glycerol using fungal culture
Omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA, C20:5, n-3) and docosahexaenoic acid (DHA, C22:6, n-3), have many medically established benefits against cardiovascular diseases, cancers, schizophrenia, and Alzheimer's. Currently, fish oil is the main source of omega-3 fatty acids, …
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Evaluation of the competitive performance of an indigenous eicosapentaenoic acid producing microalgal isolate
Omega-3 fatty acids are known to have positive effects on brain function, as well as cardiovascular disease and inflammatory diseases. They currently sold as fish oil concentrates. The fish oil extraction processes are unsustainable due to the diminishing fish stocks in open waters. In addition to …
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Eicosapentaenoic Acid (EPA) from Porphyridium Cruentum: Increasing Growth and Productivity of the Microalgae for Pharmaceutical Products
… diet is an adequate intake of omega-3 specially eicosapentaenoic acid (EPA). In the present study, the effects of two temperatures (16°C & 20˚C) and light intensities (140 & 180µE/M2.S) and four nitrate levels (0.075, 0.3, 0.5 and 0.7g/L) on the cell growth and lipid productivity of Porphyridium …
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Studies to determine the mechanisms of the anti-atherosclerotic effects of eicosapentaenoic acid: possible role for endocannabinoids?
The ω-3 polyunsaturated fatty acids (ω-3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been shown to have cardioprotective and antiatherosclerotic actions. While it has been proposed that ω-3 PUFAs may structurally stabilise atherosclerotic lesions, the underlying …
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The effect of eicosapentaenoic acid on brain and platelet produced bioactive lipid mediators. The effect of eicosapentaenoic acid, docosapentaenoic acid and other polyunsaturated fatty acids on the eicosanoids and endocannabinoids produced by rat brain and human platelets using electrospray ionisation tandem mass spectrometry-based analysis.
Eicosapentaenoic acid (EPA) is a polyunsaturated fatty acid (PUFA) with neuroprotective and cardioprotective properties. It is thought that some of the actions of EPA may be attributed to its elongated metabolite, the PUFA docosapentaenoic acid (DPA). Docosahexaenoic acid (DHA) and arachidonic acid …
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The effect of cis-5,8,11,14,17-eicosapentaenoic acid upon the contractile mechanisms linked to calcium influx and the mobilisation of intracellular calcium in aortic smooth muscle
… studies previously identified cis-5,8,11,14,17-eicosapentaenoic acid (EPA) as the biologically active component of fish oil of benefit to the cardiovascular system. Although clinical investigations demonstrated its usefulness in surgical procedures, its mechanism of action still remained …
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The Development of a Thermodynamic Model for Antisense RNA Design and an Electro-transformation Protocol to Introduce Auxotrophic Genes for Enhancing Eicosapentaenoic Acid Yield from Pythium irregulare
Eicosapentaenoic acid (EPA, C20:5, n-3) is a long chain crucial unsaturated fatty acid, essential for the regulation of critical biological functions in humans. Its benefits include the therapeutic treatment of cardiovascular disease, schizophrenia and Alzheimer's disease. The fungus Pythium …
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Evaluating fish meal as a protein source for lactating dairy cows
… Plasma long-chain n-3 polyunsaturated fatty acids were increased with increased fishmeal intake. Mammary slices from lactating bovine mammary gland were incubated with eicosapentaenoic acid. Changes in ¹⁴C-acetate metabolism were measured. Acetate oxidation and incorporation into milk lipid …
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The anabolic and anti-catabolic effects of long-chain omega-3 polyunsaturated fatty acid supplementation on functional muscular outcomes.
Long-chain omega-3 polyunsaturated fatty acids (LC n-3 PUFAs) are associated with multiple benefits, primarily related to cognitive and cardiovascular health. Recently, LC n-3 PUFAs, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have received considerable attention from the athletic …
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The effect of free fatty acids on endothelial cells
… molecules e.g. oxidized polyunsaturated fatty acids (PUFAs), or saturated free fatty acids (FFA) are alone sufficient to decrease endothelial cells. This hypothesis was tested by incubating porcine aortic endothelial cells (PAECs) with various oxidized PUFAs and saturated FFAs. Twenty hour …
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Use of Omega-3 Fatty Acids to Reduce the Risk of Cardiovascular Disease in Type 2 Hispanic Diabetics in Northeast Tennessee.
… population is at an increased risk for CVD. Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) in fish oil have been found to reduce risk of CVD. Subjects were randomly divided into two groups and received either two grams of fish oil or corn oil (control) per day for 90 days. Before …
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Isolation and characterisation of toxins from Fibrocapsa japonica (Raphidophyceae)
… finally as 6,9,12,15-octadecatetraenoic acid, all-cis-5,8,11,14,17-eicosapentaenoic acid and all-cis-5,8,11,14-eicosatetraenoic acid by HPLC-MS, IR, GC-(HR)MS, NMR experiments and biotest.
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Quantification of fatty acids over the gametogenic cycle of striped bass (Morone saxatilis) with varying dietary levels of DHA, EPA and AA
… the effects of dietary treatments on the fatty acid composition of striped bass (Marone saxatilis) blood, liver and ovary over the course of the gametogenic cycle. Striped bass were fed experimental diets in which docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and arachidonic acid (AA) …
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The effects of Omega-3, Omega-6 Polyunsaturated Fatty Acids (PUFAs) and Vitamin E on patients with the remitting-relapsing (RR) form of Multiple Sclerosis (MS) in Cyprus
… Omega (ω)-3/ω-6 polyunsaturated fatty acids (PUFAs) and some vitamins have been shown to reduce the number and severity of relapses and the overall progression of disability in multiple sclerosis patients, however clinical trials remain inconclusive due to a plethora of reasons. In this …
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Regulation of n-3 PUFA biosynthesis in proliferating and differentiated PC12 pheochromocytoma cells
Regulation of polyunsaturated fatty acid (PUFA) biosynthesis in proliferating and NGF-differentiated PC12 pheochromocytoma cells deficient in n-3 docosahexaenoic acid (DHA, 22:6n- 3) was studied. A dose- and time dependent increase in eicosapentaenoic acid (EPA, 20:5n-3), docosapentaenoic acid …
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Desenvolvimento de um sistema terapêutico emulsionado para uso oral a base de óleo de rã-touro (Rana catesbeiana Shaw)
… The bullfrog oil was characterized and peroxide, acidity, iodine and saponification values were respectively 1.92 meq O2 / kg; 2.95 KOH / g oil; 104.2 g of I / 100 g oil and 171.2 mg KOH / g of oil. The gas chromatography-mass spectrometry (GC / MS) was used to determine the compounds present in …
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Effect of Fatty Acid Modification on Prostacyclin Production in Cultured Human Endothelial Cells (Arachidonate, Elcosapentaenoate)
… to compare the effects of endogenous arachidonic acid (AA) and eicosapentaenoic acid (EPA) on prostacyclin synthesis. Supplemental levels of fatty acids (20-150 (mu)M) were supplied as sodium salts bound to bovine serum albumin (3:1 mole ratio) and added to M-199 with 20% fetal bovine serum. Both …
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Development of Omega-3-Fatty Acid Enriched Finishing Feed and Value Added Tilapia Product
… ratios and low omega-3 content specifically eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid. The objective of this study was to create an omega-3 enriching feed that would increase omega-3 content in tilapia and subsequently decrease the omega-6:3 ratio. An 8 week …
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