Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"efficacy and mechanisms"”.
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Investigation of the anti-breast cancer efficacy and mechanisms of disulfiram
I Abstract Cancer is a major cause of morbidity and mortality affecting populations in all countries and all regions. Breast cancer (BC) is the second leading cause of cancer death among women in the UK. Although the overall survival of BC has been significantly improved due to systemic therapy in …
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Investigation of efficacy and mechanisms of action in mesenchymal stromal cell therapy for chronic lung diseases
… multipotent cells that possess self-‐renewal and regenerative capacities, with the ability to differentiate into a variety of cell types. They have potent immunosuppressive abilities, facilitating the use of allogeneic MSC as a cellular therapy. Functionally, it is the trophic mediated effects …
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Inactivation mechanisms of human norovirus surrogate Tulane virus by peracetic acid at different pHs
… illnesses caused by viruses are spread by water and fresh products, hence it is critical to inactivate viruses in the water disinfection and food sanitation process. To apply a novel disinfectant requires studies to fully explore the inactivation efficacy and mechanisms of that new disinfectant. …
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Investigation of insulin releasing and glucose lowering effects of extract of selected plants used in African traditional medicinal practice
… Vernomia amygadalina, Moringa oleifera and Gongronema latifolium have been used traditionally in the treatment of diabetes globally, especially in developing countries where there is little or no access to drugs. However, information about the efficacy and mechanisms underlying …
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Identifying and characterizing fungal pathogens causing seedling diseases on soybean through a multi-state survey
Seedling diseases are both common and destructive on soybean, Glycine max (L.) Merr. They are caused by a variety of plant pathogens including fungi, bacteria, and oomycetes. The goal of this research was to identify fungal pathogens causing seedling diseases of soybean through a multi-state …
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Investigating the influence of dietary fiber source and multicarbohydrase supplementation on digestibility, energy, systemic health, water balance, and gut motility in gestating sows
… in grow-finish pig diets can improve energy and nutrient digestibility and gastrointestinal function of growing pigs. However, research on their effectiveness in gestation diets is limited. The experimental objective was to evaluate the efficacy and mechanisms associated with …
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Comparitive activities and mechanisms of action of three novel antiulcer agents
… of drugs to be discovered in recent years; and moreover, there are currently four such agents in the world list of top 25 best selling drugs. Histamine H2 antagonists have been the number one selling pharmaceutical product for more than a decade and inhibitors of the parietal cell …
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Integrated cellular, proteomic and metabolite analysis of argyrin B with rational design approaches for immunoproteasome-selective inhibitors
… a critical role in cellular protein degradation and homeostasis. Current proteasome inhibitors (PI) present great efficacy against haematologic cancers due to the high secretory load creating an increased dependency on proteostasis, yet resistance and adverse effects persist. The immunoproteasome …