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Showing 1 to 20 of 58 for “"effector protein"”.

  1. Modulation of host phosphatidylinositol phosphates by salmonella effector protein SOPB

    Piscatelli, Heather L

    … a needle-like complex composed of over 20 proteins that translocates effector proteins directly into the host cell cytosol. <em>Salmonella</em> possess a second type III secretion system encoded on <em>Salmonella</em> pathogenicity island 2 (SPI2) that secretes effector proteins involved in …

    purdue-thes Repository record

  2. Identification of host proteins targeted by the flax rust effector protein AvrL567

    Koeck, Markus2012

    … to identify cellular targets of the two M. lini effector proteins AvrL567 and AvrM and elucidate the function of these targets. To identify targets of the effector proteins, Yeast-2-Hybrid (Y2H) screens were performed with cDNA from rust infected flax leaves. This approach allowed for the …

    aus-cath Repository record

  3. Identification of host proteins targeted by the flax rust effector protein AvrL567

    Koeck, Markus2012

    … to identify cellular targets of the two M. lini effector proteins AvrL567 and AvrM and elucidate the function of these targets. To identify targets of the effector proteins, Yeast-2-Hybrid (Y2H) screens were performed with cDNA from rust infected flax leaves. This approach allowed for the …

    anu Repository record

  4. The C. trachomatis effector protein TepP hijacks host cell signaling pathways to promote bacterial survival during infection.

    Carpenter, Victoria Kay2017

    … III secretion mechanism to deliver bacterial effector proteins directly to the host cell cytoplasm. These effectors are thought to be the principle actors involved in co-opting host cell functions. TepP is an effector protein that is pre-loaded into infectious Chlamydia particles, and that is …

    duke Repository record

  5. Investigation into the function of Pi17316, a novel effector protein from <i>Phytophthora infestans</i> that compromises plant immunity

    Murphy, Fraser StuartUniversity of Dundee2017

    … differences are exemplified by pathogen effectors that manipulate processes inside the host cell to benefit colonisation. Knowledge of how these effectors and their targets function is crucial to develop strategies to enhance crop resistance. This project focuses on one such effector, …

    dundee Repository record

  6. Histidine Folding Switch In Effector Protein Avrpto Regulates Its Transport Through The Bacterial Type Iii Secretion System, As Determined By Nmr, Fluorescence, Circular Dichroism Spectroscopies And Translocation Assays

    Seckute, JolitaCornell University2011

    … conduits into host cell cytoplasm for bacterial effector protein trafficking to further their symbiotic or pathogenic goals, while avoiding detection and host immune responses. Gram-negative bacterium Pseudomonas syringae uses the type III secretion system that spans bacterial membranes and …

    cornell Repository record

  7. Regulation of the Heterochromatin Protein 1 by Phosphorylation of Histone H3 and the HP1 Hinge Domain

    Dormann, Holger

    … formed from DNA, histones, and associated proteins, is the physiological form of genetic information in all eukaryotic cells. Posttranslational modification of histones, such as acetylation, methylation, and phosphorylation, regulates various DNA-dependent processes, ranging from …

    rockefeller Repository record

  8. Moessbauer Study of Reduced Putidaredoxin in Zero and Intermediate Applied Fields

    Valentine, MarkUniversity of Illinois at Urbana-Champaign2015

    … reduced (S = 1/2) active center of the redox and effector protein, putidaredoxin, is reported. Putidaredoxin is a prototype of a 2Fe-2S protein; it functions as an electron shuttle in a bacterial enzyme system. Several 2Fe-2S proteins, including putidaredoxin, have already been subjected to …

    uiuc Repository record

  9. Virulence associated functions and vaccine potential of the burkholderia mallei type three secretion effector BopA

    Gregory WhitlockThe University of Texas Medical Branch2008

    … as type III, which is used to deliver bacterial (effector) proteins into host cells to modulate immunological and cellular responses. The intracellular survival of B. mallei within murine macrophage J774.2 cells requires the type III secretion system (TTSS), although the effector protein(s) …

    utmb Repository record

  10. A Systems Biology Approach to Study Type III and Type IV Bacterial Effector Properties

    Weigele, Bethany Auten2016

    … between Type III and Type IV bacterial effector proteins and host signal transduction enzymes is a critical interface that, in many cases, determines the outcome of infectious disease. While many pathogenic strategies, such as evasion of phagolysosomal fusion, have been identified as …

    utswmed Repository record

  11. HOOKLESS1 REGULATES RESPONSES TO PATHOGENS AND ABSCISIC ACID THROUGH INTERACTION WITH MEDIATOR18 AND ACETYLATION OF WRKY33 AND ABI5 CHROMATIN

    Liao, Chao-Jan

    … syringae DC3000 strain expressing the effector protein AvrRpm1 strain. We show that HLS1 modulates the expression of WRKY33 gene, a known defense regulator, as well as ABI5 in modulating ABA signaling pathway. The regulation of WRKY33 and ABI5 is through histone H3 acetylation (H3Ac) at …

    purdue-thes Repository record

  12. An expanded search for RNA-programmable genomic engineering effectors

    Smargon, Aaron AndrewMassachusetts Institute of Technology2016

    … Interspaced Short Palindromic Repeat) single effectors, akin to the revolutionary genome-engineering tools Cas9 and Cpf1. Whereas previous search strategies relied on protein proximity to CRISPR-associated spacer acquisition proteins Cas1 and Cas2, this approach was seeded on CRISPR arrays …

    mit Repository record

  13. The Characterization of Quorum Sensing E. Coli Regulators E,F, and G (Qse EFG) and Their Role in Pathogenesis

    Reading, Nicola Catherine2010

    … (LEE), including a type III secretion system, an effector protein, Tir, and the outer membrane protein, Intimin. Also, a prophage encoded effector protein, EspFu, is required. EHEC regulates many of its virulence genes including the AE lesion genes in response to environmental signals. Utilizing …

    utswmed Repository record

  14. Regulation of miRNA degradation

    Kingston, Elena RuthMassachusetts Institute of Technology2021

    … RNAs that repress gene expression by guiding the effector protein Argonaute (Ago) to complementary sites in the 3′ UTRs of target genes. The levels of a miRNA in a given cell-type are determined by the balance of its rates of production and decay. Although much is known about miRNA production, …

    mit Repository record

  15. Identification and Characterization of Effectors/Binding Molecules for the Small GTPase Rab15

    David Jay StrickThe University of Texas Medical Branch2005

    … turn\r\nregulates the recruitment of downstream effector molecules directly involved in\r\nmembrane transport steps. This dissertation focuses on the endocytic GTPase Rab15.\r\nRab15 localizes to early and pericentriolar recycling endosomes, and differentially\r\nregulates receptor transport at …

    utmb Repository record

  16. Characterization of the roles of Xrn1p in small-RNA-mediated gene-silencing pathways

    Getz, Matthew Aaron.Massachusetts Institute of Technology2019

    … (siRNAs). These siRNAs are then loaded into an effector protein Argonaute forming the RNA-induced silencing complex (RISC). RISC is then able to silence its target RNAs in a variety of fashions, including by slicing them. RNAi is ubiquitous in eukaryotes with pathways found in plants, animals …

    mit Repository record

  17. Characterization of 16B09 and 2D01 effector proteins in cyst nematodes

    Lin, MarriamUniversity of Missouri--Columbia2016

    Cyst nematodes use stylet-secreted effector proteins to modify a selected host cell into an elaborate feeding cell. The function of the novel effector proteins 16B09 and 2D01 from the soybean cyst nematode (SCN) Heterodera glycines and sugar beet cyst nematode (BCN) H. schachtii was studied. This …

    missouri Repository record

  18. A genetic screen to identify novel Helicobacter pylori virulence factors using Saccharomyces cerevisiae as a model eukaryotic cell

    Bothwell, Amelia M.

    … (cag PAl) that encodes and secretes the CagA protein into host epithelial cells via a type IV secretion system. To date, CagA is the only identified effector protein of the cag PAI. The goal of this study was to identify novel H pylori virulence factors, to further elucidate their role in H …

    eastern-wash Repository record

  19. Ruolo della PLCγ1 e della PKCε nel differenziamento miogenico

    Gaboardi, Gian Carlo <1978>Alma Mater Studiorum - Università di Bologna2008

    Phospholipase C (PLC) has been known to be a key effector protein in signal transduction pathway for cell proliferation and differentiation. Studies on signalling through the insulin/IGF-1 receptors in muscle differentiation have revealed that PLCγ1 is involved during this process and that both …

    bologna Repository record

  20. Mechanisms underlying rapid activity-dependent structural plasticity at Drosophila neuromuscular junctions

    Piccioli, Zachary D. (Zachary David)Massachusetts Institute of Technology2014

    … the BMP type 11 receptor Wit signals through the effector protein LIM domain kinasel (Limk) to regulate bouton budding. Limk interfaces with structural plasticity by controlling the activity of the actin depolymerizing protein Cofilin. Expression of constitutively active or inactive Cofilin in …

    mit Repository record

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