Global ETD Search
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Showing 1 to 2 of 2 for “"edema toxin"”.
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Anthrax toxin effects on B lymphocyte function
… a number of virulence factors of which, the two toxins are of great importance. Lethal toxin is a zinc metaloprotease that cleaves the N terminus of the mitogen-activated protein kinase (MAPK) kinase family 1-7, with the exception of MEK5. This kinase family is responsible for activating the …
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Host response of lung cells to virulent Bacillus anthracis
… via apoptosis. \r\n B. anthracis produces edema toxin (EdTx), an adenylate cyclase that increases cAMP levels in host cells. EdTx significantly suppressed human alveolar MØ phagocytosis of Ames spores, accompanied by cytoskeletal changes such as decreased cell spreading and F-actin content. …