Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"eculizumab"”.
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Anti-GD1a antibody targeted disruption of the node of Ranvier in a mouse model of acute motor axonal neuropathy
… of staining by the complement inhibitor Eculizumab and the calpain inhibitor AK295. A similar disruption to nodal protein staining is also shown at the proximal NoR of the desheathed phrenic nerve. Extracellular nerve recordings demonstrate a detrimental effect on function as there is a …
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Studies of EHEC and the complement system in renal diseases
… knowledge this is the first patient treated with eculizumab, an anti-C5 antibody blocking the terminal complement cascade, in the absence of kidney tissue. In summary this thesis defined novel mechanisms of pathogenesis and treatment of severe renal conditions.
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Managing alloimmunization, delayed hemolytic transfusion reactions, and hyper-hemolysis in sickle cell disease
… such as intravenous immunoglobulins, steroids, eculizumab, and tocilizumab have shown to improve outcomes in DHTR. However, these treatments may prove to be insufficient. Moreover, numerous adverse health effects are associated with using immunosuppressants, including exacerbation of …