Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 53 for “"early-response"”.
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Microfluidic devices for studying early response of cytokine signaling
… well-controlled and reproducible conditions at early stages, and detecting the protein signals with an immunocytochemical (In-Cell Western) assay. These microfluidic devices take advantage of microfabrication techniques to create an environment suitable for cell culture, biomechanical and …
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Early-Response-Prädiktion bei depressiven Patienten anhand von Psychopathologie und Therapeutischem-Drug-Monitoring
… kann gezeigt werden, dass sich die Variable Early- Response als psychopatholgischer Parameter im Sinne eines Prädiktors für das Outcome einer Response und Remission unter SNRI-Venlafaxin Behandlung nutzen lässt. Es ist weiterhin nachgewiesen worden, dass es einen signifikanten Zusammenhang …
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The Immediate Early Response of Proliferating Myoblasts to One Bout of Electrical Stimulation
The maintenance of muscle mass is important across the lifespan. The activation of satellite cells, followed by their proliferation and subsequent differentiation is important in this maintenance. Cell cycle arrest must precede differentiation, and preservation of the molecular networks involved …
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Characterization and quantification of urinary metabolic biomarkers for early response to anti-tuberculosis treatment
… of treatment outcome in TB patients at early time points would facilitate movement of new therapies through clinical trials. Previously, liquid chromatography-mass spectrometry (LC-MS) based metabolomics experiments identified potential biomarkers for early response to anti-TB treatment. …
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Early treatment expectancy and credibility as predictors of outcome, dropout and early response in Behavioral Activation treatment for depression
… frequently examined in relation to dropout and early response. The present study examined expectancy and credibility, measured after one session, in relation to (a) treatment outcomes, including depressive and anxiety symptoms, quality of life, remission, and response rate, (b) dropout, and (c) …
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Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuli
The promoters of immediate early genes (IEGs) are rapidly activated in response to an external stimulus. These genes, also known as primary response genes, have been identified in a range of cell types, under diverse extracellular signals and using varying experimental protocols. Genomic dissection …
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Correlation of urinary mcp-1 and tweak with renal histology and early response to therapy in newly biopsied patients with lupus nephritis in cape town, South Africa
… class, monitoring flares and assessing response to therapy. We assessed the utility of urinary MCP-1 (uMCP-1) and TWEAK (uTWEAK) in predicting renal histological findings, disease flares and treatment response 6 months following initiation of treatment for LN in newly biopsied patients. …
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XvERD15, an early-responsive gene to stress from Xerophyte viscosa
Genes that are upregulated in the early response to stress are not well understood. ERD15 (early-responsive to dehydration) in Arabidopsis and its homologues in various other plants have been shown to be upregulated within I hr post-exposure to dehydration and high salinity stress treatments. There …
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Multi-modal molecular imaging of radiation therapy response in the tumour vascular microenvironment
… have shown that PAI could be used to assess response to radiation therapy and chemo-radiation therapy based on changes in the tumour vascular architecture and blood oxygen saturation, which are closely linked to tumour hypoxia. Given the strong relationship between hypoxia and …
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ANALYSIS OF VARIATIONS IN SUSCEPTIBILITY AND TRANSCRIPTOME RESPONSES IN TOMATO TO TWO-SPOTTED SPIDER MITE FEEDING
… and susceptible tomato cultivar transcriptiome responses to mite feeding. Cultivars were screened for mite resistance using a platform developed and presented in this thesis. MicroTom (a brassinosteroid biosynthesis mutant) was found to be resistant to mite feeding, while MicroTom-D (a near …
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Early Intervention In Suspected Sepsis Patients
… Inform the development and implementation of an early response algorithm for suspected sepsis patients via a rapid response team. </p> <p>Background: Recent literature supports the need for early recognition and intervention of suspected sepsis patients, potentially reducing morbidity and …
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Molecular analysis of the responses of Caenorhabditis elegans (Bristol N2), Panagrolaimus rigidus (AF36) and Panagrolaimus sp. (PS 1579) (Nematoda) to water stress
… a comparative and genetic analysis of the responses to water stress in desiccation-tolerant and desiccation-sensitive nematodes. Caenorhabditis elegans, a model organism for the study of development, aging, and cell biology was shown to be a desiccation-sensitive organism that survives …
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Identification of the Downstream Effector Genes Involved in HOXB4-Induced Expansion of Hematopoietic Progenitor Cells
… genes with differentially changed expression in early response to HOXB4 have been identified as candidate target genes. Among them, we show that <em>Hemogen</em> (<em>Hemgn</em>), encoding a nuclear protein specifically expressed in hematopoietic stem and progenitor cells, is a direct …
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Quantifying and evaluating the risk posed to straw bale constructions from moisture
… The concept of the model is to provide an early response mechanism to warn of the potential of adverse effects and thereby averting the need for destructive investigation and remedial action.
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Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors In Breast Cancer
… with LMW-E expressing tumors show diminished early response to neo-adjuvant AIs as well as poor recurrence-free survival. In addition, xenografts with LMW-E expression are unresponsive to letrozole. Using LMW-E inducible model system, we show that LMW-E expression bypasses cell cycle …
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Bedeutung der IL-6-Signaltransduktionsinhibitoren SHP2 und SOCS3 für die Desensitisierung des IL-6-Signalweges
The immediate early response of cells treated with IL-6 (interleukin-6) is the activation of the signal transducer and activator of transcription (STAT) 3. The Src homology domain 2 (SH2)-containing protein tyrosine phosphatase SHP2 and the feedback inhibitor SOCS3 (suppressor of cytokine …
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Regulation of ethylene biosynthesis by mitogen-activated protein kinase cascades in Arabidopsis
… effects on plant growth, development, and response to environmental stimuli. Ethylene induces the ripening of climacteric fruits, which is characterized by a steep increase in ethylene synthesis at the mature stage. In agriculture, removal of ethylene in hypobaric storage compartments …
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SURVIVING UNDER PRESSURE: TRANSLATIONAL REWIRING IN RESPONSE TO MECHANICAL STIMULI
… similar mechanisms may play a role in the responses of tumor cells upon mechanical stress. To shed light on the mechanisms, we have employed several approaches to study the acute alterations in cell size induced by mechanical stress. We used osmotic shocks and compressive stresses, as well …
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Cortical Pyramidal Neuron Subtype Classification and Visual Response Diversity
… by measuring passive neuronal properties and responses to current injection using whole-cell patch-clamp recordings. A blind clustering algorithm exercised on the data revealed the presence of two principle classes of neurons.To address functional profiles, we recorded visual responses of …
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Television Without Frontiers
… European context can be read as an early response to this predicament.
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