Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"early gene (IEG)"”.
-
Analysis of Immediate-Early Gene Expression in the Songbird Brain Following Song Presentation
… are involved, the expression of an immediate-early gene (IEG) was studied. The isolation of the canary ZENK homologue is described, an IEG that encodes a zinc-finger protein and which is highly sensitive to growth factors and depolarizing stimulation, including stimuli leading to LTP induction …
-
Hormonal mechanisms for variation in female mate choice
… involved in phonotaxis behavior. Immediate early gene (IEG) induction, specifically egr-1, was used to mark neuron activity. Females were treated with either HCG or saline and exposed to either mate choruses or silence. Egr-1 expression was quantified in an auditory midbrain nucleus, the …
-
Examining cholinergic fuction in the ventral tegmental area and dorsal hippocampus
… points analysed. There was no evidence of neurodegeneration (as measured by Fluoro-jade C) present in the pVTA, PPTg or LDTg. A non-lesion approach was also adopted to better understand the actions of cholinergics in the pVTA. The effects of nicotine self-administered into the VTA or (as a point …
-
Forebrain Acetylcholine in Action: Dynamic Activities and Modulation on Target Areas
… that putative MS cholinergic neurons may be a generalized hippocampal activation/arousal network. </p><p> Third, I investigated the hypothesis that ACh enhances cortical and hippocampal immediate-early gene (IEG) expression induced by novel sensory experience. Cholinergic transmission was …
-
Dynamic Modulation of an Immediate -Early Gene in the Songbird Forebrain
"In the nervous system, immediate-early gene (IEG) induction is observed following exposure to salient events. Although the function of IEGs is not fully understood, one prominent model suggests that they are needed to consolidate memories of the inducing event---a ""feed-back"" model. However, a …
-
Response Modulation by Single Units in the Auditory Neostriatum of Songbirds: Characterization of Responses and Their Relationships to Nuclear Gene Regulation in Adult and Juvenile Zebra Finches
"Presentation of birdsong activates immediate early gene (IEG) expression in the caudomedial neostriatum (NCM) of songbirds that are at least 30 days of age (d30) (Mello, et al., 1992; Jin & Clayton, 1997). However, when songbirds are raised in isolation, playback of birdsong fails to induce these …
-
Neuropathological role of alpha-synuclein: major contribution of inflammation in the evolution of both motor and non-motor symptoms of Parkinson’s disease
… times/week for two months) was tested in the early stage of the disease. We found that the infusion of H-αSynOs induced an impairment in motor performance that was fully rescued by Pom, as assessed via a battery of motor tests. Moreover, H-αSynOs-infused rats displayed a 40–45% cell loss …