Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"eIF6"”.
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INTEGRATED TRANSCRIPTOMIC AND TRANSLATIONAL PROFILING OF EIF6-SBDS IN SHWACHMAN-DIAMOND SYNDROM REVEALS DIFFERENT CELLULAR STATES SHAPED BY RIBOSOME COMPOSITION AND FIDELITY
… for release of the anti-association factor eIF6 from nascent 60S subunits, a prerequisite for productive 80S assembly and translational initiation. Consequently, SBDS deficiency limits the pool of functional ribosomes and constrains global protein synthesis. Recent sequencing of SDS bone …
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Dissecting SBDS function in Arabidopsis thaliana
… the zinc finger domain of AtSBDS interacts with eIF6, similar to homologues Rei1 and Vms1, potentially contributing to its eviction from the 60S ribosomal subunit as part of a ribosome quality control system. Furthermore, I propose that this domain plays a critical role in ribosome biogenesis and …
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COMPUTATIONAL MULTISCALE INVESTIGATIONS OF BIOLOGICAL MOLECULES
… of domains II-III and the detachment of eIF6 from the 60S subunit. Furthermore, the study highlights the structural similarity of the K67E mutation to the wild type, despite a lower exposed positive charge. This finding, supported by free energy analysis, suggests that the pathological …