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Showing 1 to 2 of 2 for “"eIF4E-independent"”.
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Elucidating the Roles of Eukaryotic Initiation Factors Involved in DAP5 Mediated Translation
… which consists of the cap binding protein eIF4E, the scaffolding protein eIF4GI, and the helicase factor eIF4A.The recognition and binding of eIF4E to the m<sup>7</sup>G cap structure of the mRNA is essential for the subsequent recruitment of eIF4GI and eIF4A to form a translationally …
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Assessing eIF4E-S209 Signaling and Translationally Regulated Mechanisms in Neurodegeneration
… eukaryotic translation initiation factor 4E (eIF4E). Downstream of stimuli, ERK or p38 can phosphorylate the MAPK interacting serine/threonine kinases (MNKs) 1 and 2. MNK1 or 2 then phosphorylate eIF4E, at a specific residue; serine 209 (S209). Phosphorylation of eIF4E-S209 by the MNKs can …