Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"eIF4B"”.
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Eucaryotic Initiation Factor 4b of Wheat Germ Binds to the Translation Initiation Region of Satellite Tobacco Necrosis Virus Ribonucleic Acid (Rna)
… binding assays with a K(,d) = 1 x 10('-7)M. EIF4B also binds the 5'-terminal 52 nucleotides of STNV {5'- ('32)P}RNA (i.e., the translation initiation site of STNV RNA) with the same efficiency as intact STNV {5'- ('32)P}RNA, but does not bind control samples of randomly selected 5'- ('32)P 52 …
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Combating Resistance To Epidermal Growth Factor Recpetor Inhibitors In Triple Negative Breast Cancer
… the translational control pathway, specifically, eIF4B as a potentially key regulatory point in EGFR and mTOR inhibitor synergy. Further, we have also identified the transcription factor, STAT3 as another regulatory point in the EGFR and mTOR inhibitor synergy. Therefore, in this study we …
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The Interaction Between Eukaryotic Translation Initiation Factor eIF4G and 3’ Cap Independent Translation Element of Barley Yellow Dwarf Virus Is Affected by Multiple Initiation Factors
… binding domains for eIF4E, central eIF4A, eIF4B and the possible BTE binding region; eIF4G601-1488 is a longer fragment with one additional C-terminal eIF4A binding domain; eIF4G742-1196 is a shorter deletion mutant lacking the eIF4E binding sequence. eIF4G601-1196 binds BTE as efficiently …
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Factors That Mediate Expression Of Unique Ggggcc Repeat Expansions In C9orf72-Associated Als/ftd.
… targeted screen. Follow-up studies revealed that eIF4B and eIF4H knockdown reduced GR-peptide levels produced from G4C2-transcripts and G4C2-toxicity in the fly, defining them as potential RAN-translation factors in C9+ disease. In summary, jumping from unbiased forward genetic screens in …
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Direct Recruitment of eIF4GI and/DAP5 to the 5' UTR of a Subset of Human mRNA Drives Their Cap-independent Translation
… for the additional initiation factors (eIF4A, eIF4B and eIF4E) required by these mRNAs for their cap-independent translation initiation, adding to our understanding of these different cap-independent translation mechanisms. Collectively, the quantitative binding- and <em>in vitro</em> …