Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 150 for “"dysplasia"”.
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Microultrasound Imaging of Tissue Dysplasia
The second most common cause of cancer deaths in the developed world is bowel cancer. Improving the ability to detect and classify lesions as early as possible, allows treatment earlier. The work presented in this thesis is structured around the following detailed aims:Development of high …
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Characterizing Human Papillomavirus Associated Oral Epithelial Dysplasia
… We identified HPV-associated oral epithelial dysplasia (HPV-OED) through screening for histopathological features of HPV and p16INK4a immunoreactivity. Transcriptionally active infections were confirmed by performing RT-qPCR to identify E6 mRNA expression. We identified 82 cases of confirmed …
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Ceramides as Therapeutic Targets in Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) is a chronic lung disorder associated with extremely premature birth, resulting from arrested development of the microvasculature and consequently disrupted alveologenesis. Premature infants are dependent on respiratory support, including oxygen supplementation and …
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Detecting cervical dysplasia with quantitative spectroscopic imaging
… develop a QSI system capable of imaging cervical dysplasia in vivo. Using the QSI system, we conduct a clinical study to train and prospectively evaluate QSI's ability to distinguish high-grade squamous intraepithelial lesions (HSIL) from non-HSILs (less severe conditions) in cervical …
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Quantitative spectroscopy for detection of cervical dysplasia
The current clinical standard for cervical cancer diagnosis is colposcopy, a procedure that involves visual inspection and biopsy of at-risk tissue, followed by histopathology. The major objective of colposcopy is detection of high-grade squamous intraepithelial lesions (HSIL), which are …
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Fibroottinen dysplasia pään ja kaulan alueella : systemaattinen kirjallisuuskatsaus
Fibroottinen dysplasia on hyvänlaatuinen luuston harvinaissairaus. Taudinkuvassa alkionkehityksen aikainen mutaatio johtaa luun kehityshäiriöön ja luunsisäisten sidekudospesäkkeiden muodostumiseen. Fibroottinen dysplasia voi esiintyä yhdessä tai useammassa luussa, ja siitä tunnetaan myös …
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Characterization of mucosal dysplasia with ultraviolet resonance Raman spectroscopy
Thesis (Ph. D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 1997.
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Abduction Contractures within Infants with Developmental Dysplasia of the Hip
<p>Developmental Dysplasia of the hip is a condition that affects 1 to 3 of every 1000 infants born globally. It is a pathology that involves the instability, subluxation, or dislocation of the femoral head from the acetabulum. Through a rating system by the International Hip Dysplasia Institute or …
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Friction Ridge Dysplasia and Its Preponderance in the Afghanistan Population
<p>Friction Ridge Dysplasia is a rare genetic disorder in which the friction skin ridge units do not fuse together to form continuously flowing friction ridges. The skin affected by Friction Ridge Dysplasia is generally localized to one area and gives a similar appearance of the pebbled state of …
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Defining the Cellular and Molecular Basis of Spondyloepiphyseal dysplasia tarda
… a rare Mendelian disorder, Spondyloepiphyseal dysplasia tarda (SEDT), is caused by sedlin mutations in which the main clinical manifestation is an alteration in collagen deposition. With the aim to clarify sedlin functions in membrane trafficking, I followed two different approaches: (1) …
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Association Between New Bronchopulmonary Dysplasia and Pulmonary Hypertension in Extremely Premature Newborns
Bronchopulmonary dysplasia (BPD) is one of the most significant chronic complications of premature newborns treated in neonatal intensive care units. This thesis provides a deep review of the pathogenesis of BPD, the association of hypoxia with the development of BPD associated pulmonary …
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Development of Novel Instrumentations and Algorithms for Optical Screening of Epithelial Dysplasia
… on deep learning was presented for identifying dysplasia from depth-resolved angular scattering scans collected by a/LCI with high accuracy and speed. Future development of this algorithm may open to possibilities for real-time clinical analysis of a/LCI data, and improve the clinical utility of …
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Volumetric Optical Imaging of Tissue Microstructure for Grading of Dysplasia In Vivo
… nuclei with the progression of esophageal dysplasia. In this thesis research, we investigate the application of novel signal processing methods and custom OCT hardware to uncover biomarkers of dysplasia based on these pathological changes in cell nuclei. Further, we apply our methods to …
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The Role of Pelvic Tilt in Femoroacetabular Impingement Syndrome, Hip Dysplasia, and Osteoarthritis
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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The Efficacy and Safety of Montelukast Sodium in the Prevention of Bronchopulmonary Dysplasia
… sodium in the prevention of bronchopulmonarydysplasia(BPD) METHODS: This study was designed as a multicenter, prospective, randomized, open labelled, parallel-group, intervention study. 66 infants were enrolled and allocated to Case group (n=30) and Control group (n=36) by random assignment …
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Investigation of the GATOR1 complex genes in focal cortical dysplasia and focal epilepsy
… with familial focal epilepsy and focal cortical dysplasia (FCD) type II. Heterozygous patients are affected with variable severity, variable foci and incomplete penetrance. The function of these genes and the mechanisms of how their mutation cause the disease are not well understood. In vitro …
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Computational Investigation of the Biomechanics of Babywearing in Regards to Developmental Dysplasia of the Hip
<p>Developmental Dysplasia of the Hip (DDH) is a congenital condition where an infant’s hip socket is either loose or otherwise unstable. DDH causes a joint instability where the femoral head is not properly situated inside the acetabulum. Etiology of the condition is in part congenital and …
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