Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"dysmotility"”.
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Intragastric Mechanical Systems for Dysmotility Diagnosis and Obesity Treatment
… challenges stemming from the obesity epidemic, dysmotility evaluation and intervention to simulate satiety as a mode of therapy. Specifically, dysmotility, often associated with metabolic derangements including diabetes mellitus and obesity, can be challenging to evaluate with precision. Satiety …
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miR-10b Rescues Diabetes and GI Dysmotility Associated with a Leaky Gut
… dysfunction, impaired barrier function, and gut dysmotility play a key role in the development of metabolic disorders and disorders of gut-brain interactions (DGBIs). In reference to the Rome IV criteria, the most common DGBIs, include functional dyspepsia (FD) and irritable bowel syndrome (IBS). …
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Gastrointestinal motility and the role of gonadotropin-releasing hormone (GnRH)
… hormone (GnRH) and gastrointestinal symptoms and dysmotility. In primary Sjögren’s syndrome (pSS), a patient group with high levels of GnRH antibodies, associations between objective signs and symptoms of autonomic dysfunction (AD), impaired gastric emptying (IGE), and inflammatory and serological …
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Gastrointestinal Disorders in Women
… clostridioforme. Gastroparesis and esophageal dysmotility are common complications of diabetes mellitus in both symptomatic and asymptomatic patients. In a cross-sectional study, we evaluated esophageal and gastric motility, GI symptoms, secondary complications, and plasma biomarkers in …
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Autonomic dysfunction in primary Sjögren's syndrome
… objective signs of pharyngeal and esophageal dysmotility were not. Dysphagia in pSS patients was not related to video-radiographical signs of dysmotility but it was associated with objective signs of parasympathetic dysfunction.
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A Fundamental Investigation into the Presence of Interstitial Cells of Cajal within the Gastrointestinal Tract of Dania rerio
… with neutralizing antibodies results in GI dysmotility and loss of the electrical slow wave. Furthermore, GI dysmotility symptoms and other human pathologies have been correlated with ICC deficiencies within the GI tract. Currently, there are few treatments and therapeutic interventions for …
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The effects of rocking chair motion on postoperative ileus duration, subjective pain, pain medication use and time to discharge following abdominal surgery
… of the abdomen result in gastrointestinal dysmotility, to some extent, in all patients because abdominal surgical procedures to remove abdominal tumors require large abdominal incisions, extensive dissection, and manipulation of the bowel that initiates a surgical induced stress response …
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Three Gastrointestinal Assays
… to determine if discomfort results from a true dysmotility or from idiopathic symptoms. GI transit assays help to determine appropriate treatments but idiopathic symptoms, or pain from an unknown cause, is very common. The zebrafish is an attractive model system for human GI motility because the …
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Customizing Multifunctional Bidirectional Neural Interfaces through Fiber Drawing
… coordinated peristaltic waves and address dysmotility in the esophagus and the stomach. Taken together, the findings of this thesis are anticipated to provide a platform for multifunctional fiber-based probes development, and their application in the brain and peripheral circuits as …
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Posterior Laryngitis- Aetiology,Treatment and Health-Related Quality of Life
… (HRQOL) in patients with PL and/or oesophageal dysmotility. In paper I, a group of patients diagnosed as having PL were examined, treated and followed, to determine whether follow-up is needed. Their current HRQOL was registered. In paper II, we investigated how many of the patients diagnosed …
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Natural History of Biliary Sludge in Dogs
… sludge is associated with gallbladder (GB) dysmotility and mucus hypersecretion suggesting that these factors could lead to GB mucoceles. If biliary sludge does progress to GB mucoceles, treatments to reduce the production and progression of sludge are warranted. Objectives: The aim of this …
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Epigenetic Modification of Phenotype in Intestinal Smooth Muscle Cells
… to the thickened intestinal wall and the dysmotility symptoms observed in inflammatory bowel disease (IBD). A unique consequence of Crohn’s disease (CD), a subset of IBD characterized by chronic, transmural intestinal inflammation, is the formation of obstructive strictures attributable to …
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Differentiation and contractility of colon smooth muscle under normal and diabetic conditions
… symptoms such as constipation due to intestinal dysmotility. Mice were treated with low-dose streptozotocin to induce a type 1 diabetes-like hyperglycemia. CT scans revealed decreased overall GI tract motility after 7 weeks of hyperglycemia. Acute (1 week) and chronic (7 weeks) diabetic mice also …
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Non-invasive assessment of gastrointestinal function using breath test technology : investigations in health and disease.
… whilst a more severe stomach inflammation caused dysmotility; (2) baclofen (a potential reflux therapy) accelerated gastric emptying of solids and delayed liquid emptying in a dosedependent manner; and (3) mice with a high daily food intake had faster emptying compared to those with low intake, …
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Neuroglial differentiation and neo-innervation in extracellular matrix-based tissue engineered innervated smooth muscle sheets
… pathological states resulting in intestinal dysmotility and reduced quality of life. Neural-crest derived enteric neuronal progenitor cells persist in the adult mammalian gut, and contribute to the plasticity observed in the adult enteric nervous system. Neural stem cell transplantation is an …
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Aspects of paediatric gastro oesophageal scintigraphy
… recognition of the importance of oesophageal dysmotility in paediatrics, especially in the absence of GOR and its relevance to the efficacy of surgery in cases of apparent GOR. Also, this gastro oesophageal scintigraphic study provided information on the paediatric use of cisapride, the …
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MUSCLE-SPECIFIC MECP2 MISEXPRESSION INDUCES SKELETAL AND VISCERAL MUSCLE DEFECTS RESCUED BY BUTYRATE SUPPLEMENTATION IN DROSOPHILA
… features, including gastrointestinal dysmotility and muscle hypotonia - suggesting that MeCP2 dysfunction may also impact peripheral tissues. Since MECP2 is expressed in muscle, yet its role outside the nervous system remains poorly defined, this work explores the tissue-autonomous …
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Sympathy for the Microbiota: How Changes in Gut Microbial Composition Influence the Immune System and Basic Physiology by Way of the Sympathetic Nervous System
… and persistent loss in iEAN numbers and chronic dysmotility. Intersectional genetics, pharmacological intervention, and chemogenetic sympathetic activation was used to demonstrate that MM-specific Β2AR signaling is required to confer neuronal protection during the course of infection and prevent …