Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"dual functionality"”.
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Synthesis, Characterization, and Evaluation of Silica-Nanosphere-Based Contrast Agents for Biomedical Application
… introduced into the silica nanospheres for dual functionality. Gd-DTPA, a commonly used MRI contrast agent, was chosen as an appropriate candidate for initial study. Through an in vivo experiment using tadpoles, we demonstrated and evaluated dual functionality of Gd-DTPA loaded silica …
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Synthesis and biological evaluation of structurally diverse indole-based analogues as inhibitors of tubulin polymerization and synthesis of drug-linker constructs cleavable by enzymes present in the tumor microenvironment.
… that bind to the colchicine site demonstrate dual functionality as both potent cytotoxins (antiproliferative agents) and effective vascular disrupting agents (VDAs). Our previous studies led to the discovery of a potent inhibitor of tubulin polymerization and cancer cell growth, OXi8006, and …
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Methods for the synthesis of linear dialkylaromatic compounds by the use of heterogeneous catalysts
… The reaction is a good example of catalyst dual-functionality, where acidic and metallic sites are both required to obtain good yields. The second reaction deals with the alkylation of biphenyl and naphthalene with propylene, to shape selectively synthesize 4,4'-diisopropylbiphenyl and …
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Purification of Recombinant HIS6-GFP-Preptin Fusion Protiens
… Type 2 diabetes mellitus and osteoporosis. Its dual functionality—stimulating insulin secretion without inducing hypoglycemia and promoting osteoblast proliferation—positions it as a unique alternative to traditional sulfonylureas and osteogenic agents. In this study, we developed a purification …
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Singlet oxygen generating luminescent lanthanide complexes with naphthalimide-based and oligothiophene-based sensitizers
… these compounds as potential therapeutics with dual activity can be assessed and optimized. The complex with the highest luminescence efficiency for EuIII was [Eu(1Tdpa)3]3- (41.0%), for YbIII was [Yb1Thept(COO)4]- (0.50%), and for NdIII was [Nd2Thept(COO)4]- (0.45%). None of the water-soluble …
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H-BN integration in III-nitride devices for green hydrogen applications
… exchange membrane (PEM). Additionally, the dual functionality of h-BN is highlighted—not only as a PEM to enhance device lifetime under long-term operational conditions but also as a potential system for hydrogen storage at a micro-scale level via the formation of h-BN bubbles under UV light …
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INELASTIC ELECTRON TUNNELLING SPECTROSCOPY (lETS) OF SILANE COUPLING AGENTS
… matrix. To fulfil this function the silane has dual functionality; usually two or three hydrolysable groups and a reactive end group compatible with the coating to be used. Here, mainly trialkoxysilanes have been studied with either vinyl, amine or epoxide end groups in order to identify the …
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Advanced transfer printing methods and their applications to functional surfaces
… to enable double-sided patterned inks with dual functionality such as structural coloration or superhydrophobicity paired with external stimuli responsiveness are invented. Lastly, switchable underwater adhesive properties of a shape memory polymer that is one of common polymeric stamp …
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Coagulation and flocculation process using cassava peel starch modified with lemongrass extract for pollutants removal in raw water
… days. The present research synthesized a novel dual function coagulant using cassava peel starch with incorporation of lemongrass extract and evaluated the synergistic effect between alum and modified cassava peel starch (MCPS) or native cassava peel starch (CPS) as dual coagulants in removing …
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Method Development Towards Catalytic Transformations of Reactive Intermediates
… the active catalyst, while the silver salt had dual functionality in both activation of the palladium catalyst and stabilization of an off-cycle carbocation via pseudo-halogen scavenging.
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Development of Au-Pt Nanoflowers as Nanoenzyme for Highly Sensitive Immunoassay: Application to the Detection of Melioidosis Biomarker
… on gold nanoparticles (AuNPs) surfaces, ensuring dual functionality as signal labels. Through the use of a developed nanoenzyme, lateral flow assays for CPS were made possible using the Au-Pt NFs conjugated with anti-CPS antibodies. By only using the Au-Pt NFs without sophisticated instruments, it …
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The development of nano-sized silicas as analytical tools
… and, for organic extractions, a mixed functionality diol and C18 modification. The nanoscavengers were characterized by Fourier transform infrared spectroscopy, scanning electron microscope, transmission electron microscope and thermogravimetric analysis. Copper capacity measurements …
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Land and people in Wicklow, 1660-1840
… order in the eighteenth century, the parish had dual functionality, with responsibilities in both civil and ecclesiastical realms. It is shown that as Protestantism declined throughout Wicklow, Catholics became increasingly involved in the operation of parish structures. Furthermore, after the …
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Structural and aesthetic design applications of flexible, thin-film solar cells to power off-grid tensile structures
… the boundaries of solar panels to provide the dual functionality of energy harvesting and architectural structure, while either maintaining or improving the aesthetics of the architecture on which they are placed. To achieve this, this research explores a new use case for flexible thin-cell …
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Investigating the ablative and immunomodulatory effects of high frequency irreversible electroporation on osteosarcoma in-vitro
… tumor with an annual incidence rate of 3-4 individuals per million particularly affecting children and young adults. The 5-year survival rate stands at 60-80% with the current standard of care for human OS patients who do not have metastatic disease at presentation, but this drops to 20% for …
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Interactions between the TatBC complex and Tat signal peptides during protein transport by the bacterial Tat pathway
… study indicates that Tat signal peptides have dual functionality, to both target substrates to the Tat machinery and to trigger its assembly and that there is unprecedented overlap between Sec and Tat signal peptides.<br/>
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Catalytic conversion of biomass-derived molecules into mono- and dicarboxylic acids and esters
… zeolites suggest that Hf(IV) open sites possess dual functionality for Lewis and Bronsted acid catalysis.
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Investigations into the roles of bacterial TorD family chaperone proteins
… and again highlighted the prospect of dual functionality of these chaperone proteins, with TorD amino acid residues being implicated in TorA signal peptide interactions and TMAO reductase activity. High resolution microscopy was employed to enable imaging of TorD within the cellular …
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Studies of alkali metal compounds in diesel fuel and small molecule activation chemistry
… leading to products containing new dual imine and amide functionality at the backbone γ-carbon position. The mechanism leading to this dual functionality was explored via multinuclear NMR spectroscopic studies. Finally, extension to carbodiimides and phosphine oxide molecules …
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Regulation of macrophage subsets in homeostatic and inflammatory mucosal environments
… challenge. Mucosal macrophages (MΦs) have a dual functionality that determines tolerance to commensal organisms or immune response to entropathogens such as E. coli. In the case of mucosal inflammatory pathologies, such as Crohn’s disease, this state of tolerance is broken, resulting in …
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