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Showing 1 to 1 of 1 for “"dual endonuclease"”.
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Mechanism of Permissive Cleavage Activity of TevCas12a
We created a novel dual endonuclease called TevCas12a. TevCas12a is a fusion of the I-TevI nuclease and linker domains to Cas12a. The goal was to create a dual endonuclease that made precise double-strand breaks leaving non-compatible ends for exogenous DNA insertion and specific deletions. …