Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 27 for “"dry eye"”.
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Intense Pulsed Light for the Treatment of Evaporative Dry Eye
… factor in the development of evaporative dry eye (EDE), a common presentation in ophthalmic clinics which causes significant detrimental effects on quality of life. Traditional management strategies often fail to provide sustainable solutions, prompting patients and clinicians to seek …
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Evaluating the Role of the Ocular Surface Microbiome in Dry Eye Disease Mediated Neural Dysregulation
Dry eye disease (DED) is a multifactorial ocular surface disorder arising from a loss of homeostasis at the corneal-tear interface. This leads to visual and neurosensory abnormalities which are regulated by the corneal-trigeminal ganglion pathway. An important contributor to ocular homeostasis is …
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Pathogenesis of Dry Eye in Graft Versus Host Disease (GVHD): Role of Ocular Mucins and Conjunctival Fibrosis
… immune cells to host organs, including the eye surface. Mostly based on the time of disease onset after transplantation, GVHD is divided into the acute and chronic phase. The eyes may be involved in both acute and chronic GVHD, although ocular involvement is more common in the chronic GVHD …
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TOLL-LIKE RECEPTOR EXPRESSION AND FUNCTION
… presents from various etiologies (e.g. dry eye and Pseudomonas aeruginosa (PA) infection), yet little is known about the role of toll-like receptors (TLR) which, upon activation, stimulate inflammation. The objective of this research was to determine: (1) baseline expression of TLRs in …
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Development of Mass Spectrometric Methods for the Analysis of Components and Complex Interactions in Biological Systems
… of the fragmentation processes. The dry eye condition affects millions of individuals world wide. The symptoms can be a result of simple irritation to the eye or a serious disease state. A dry eye model was developed using rabbits in order to study the compositional makeup of the tear …
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ΔΡΑΣΕΙΣ ΤΩΝ ΓΛΥΚΟΚΟΡΤΙΚΟΕΙΔΩΝ ΣΤΟΥΣ ΝΕΥΡΩΝΕΣ ΤΟΥ Κ.Ν.Σ. ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΜΟΡΙΑΚΩΝ ΜΗΧΑΝΙΣΜΩΝ ΠΟΥ ΕΝΕΧΟΝΤΑΙ ΣΤΗΝ ΑΠΑΝΤΗΣΗ ΤΟΥ ΟΡΓΑΝΙΣΜΟΥ ΣΤΟ STRESS
… 50 PERSONS ONE WITH SUBJECTIVE SYMPTOMS OF DRY EYE, 33 WOMEN WITH CONNECTIVE TISSUES DISEASES WITHOUT SECONDARY S. SJOGREN AND 92 PERSONS WITH S SJOGREN. WE EXAMINATED THE LACRIMAL FUNCTION WITH BREAK-UP TIME, SCHIRMER-I TEST AND ROSE BENGAL STAINING AND THE CONJUCTIVAL EPITHELIUMS WITH …
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Ressecamento ocular: desenvolvimento de uma teoria de enfermagem de médio alcance
… to develop a mid-range nursing theory of ocular dryness based on Roy's adaptation model. The strategies for the development of theories proposed by Walker and Avant (2019) were adopted, choosing the concept analysis strategy for the presentation of concepts, the establishment of relational …
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Pilot Study of a Method to Objectively Measure Asthenopia Symptoms
… which may be summarized in two categories: eyestrain due to accommodative or convergence dysfunction, or eyestrain as a manifestation of dry eye. While these categories are not mutually exclusive, treatment of asthenopia has historically been limited to the use of spectacle lenses to …
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Μεταβολές της προκερατίου δακρυϊκής στιβάδος και μελέτη του επιθηλίου του επιπεφυκότα με την μέθοδο του αποτυπώματος σε φυσιολογικά και ξηρά μάτια
… 50 persons one with subjective symptoms of dry eye, 33 women with connective tissues diseases without secondary S. Sjogren and 92 persons with S. Sjogren. We examinated the lacrimal function with break-up time, Schirmer-1 test and Rose Bengal staining and the conjuctival epitheliums with …
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Photosensitizer Loaded Contact Lenses As An Externally Stimulated Ophthalmic Drug Delivery System
… millions of people suffering from anterior eye diseases like dry eye, glaucoma (3.2 million of women of the United States suffer from dry eye, nearly 2.7 million Americans suffer from Glaucoma).
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Structural and functional characteristics of meibomian glands in meibomian gland dysfunction
… contact lens wearers and participants with dry eye disease (DED). The third prospective study used multimodal imaging to evaluate MG orifices and explore their associations with, and ability to predict symptoms. The fourth study investigated inter-day and intersubject variations in meibum …
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Imaging of Meibomian Glands in Various Species
… for tear stability which is disrupted during dry eye disease. Blink rate varies across species suggesting differences in tear film stability, MG anatomy, and meibum quality. Meibography is performed on humans, but little is known about MG in other species. Using ex vivo meibography we imaged …
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Characterization of Ocular Surface Pathology and Tear Film Dysfunction Due to Type 1 and Type 2 Diabetes Mellitus
… affecting heart, nerves, kidney, and eyes. While the etiological mechanisms of diabetes-associated retinopathy and cataract have been well characterized, the time kinetics and the severity of diabetes-mediated injury to the ocular surface and its various components like tear film, …
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Biochemical studies of the tear film in humans and rabbits
… film stability has been associated with both dry eye and contact lens discontinuation. Rabbits are known to have a significantly longer inter-blink time compared to humans, perhaps due to their very stable tear film. The reason for this, however, has never been studied at a detailed …
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ANALYSIS OF MICROBIOME IN VARIOUS HUMAN MEDICAL CONDITIONS USING NEXT-GENERATION SEQUENCING OF THE 16S rRNA GENE
… were mostly prevalent in gut samples. Moreover, dry eye disease conditions were characterized by a higher prevalence of <em>Carnobacteriaceae</em>, <em>Acinetobacter</em>, and <em>Enterococcaceae</em>, whereas healthy eyes exhibited a distinct microbial composition, including the presence of …
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The effect of ageing on the morphology and physiology of the lacrimal gland
… tear production, which is associated with dry eye conditions. However, very little is known about ageing effects on the lacrimal gland and in particular the lacrimal gland acinar cells. This study employed light and electron microscopy, immunohistochemical, radiobiological and physiological …
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Development of Multifunctional Drug Delivery Systems for Locoregional Therapy
… and applied to N-94, a therapeutic peptide for dry eye treatment. The results demonstrated SiNPs system could provide controlled drug release that is also degradable under simulated physiological conditions. Building on these results, silica (SiO2) was introduced to prepare PVA-SiO2-IONP …
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Mechanisms associated with secretory and contractile responses in tissues and cells of the body in health and disease
… gastric ulcers, cataractogenisis and the dry eye syndrome) compared to healthy conditions. The results have demonstrated that, in addition to parasympathetic nerves, the pancreas, parotid and the lacrimal glands are innervated with adrenergic and non-cholinergic, non-adrenergic …
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Comparison of wettability for surface of ocular prosthesis depending on different kind of artificial tear eye drops
… depending on different kind of artificial tear eye drops. METHODS: The artificial tear eye drops that contain sodium hyaluronate (HA) 0.1%, 0.18%, 0.3%, carboxyl methylcellulose sodium (CMC), hydroxymethylcelluose+dextran (HMC), propylene glycol+polyethylene glycol (PG), polysorbate 80 (PS), …
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