Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 285 for “"drug administration"”.
-
The potential health impact of ivermectin mass drug administration for malaria control on swine in Mozambique
… trial assessing the use of ivermectin (IVM) mass drug administration to humans and pigs for the control of malaria vectors in the Mopeia district in Mozambique, a longitudinal study to assess the impact of IVM administration on pig health was performed. METHODS: Beginning in March 2022, IVM was …
-
An Economic and Regulatory Analysis of Breast Cancer Drugs Approved by the US Food and Drug Administration
… approvals and prices at the market entry of new drugs indicated for breast cancer in the period 1980-2022. The study also evaluated the factors associated with the price of the new breast cancer drugs at market entry.</p> <p><strong>Material and Methods</strong></p> <p>Regulatory data were …
-
Approval of new drugs by the U. S. Food and Drug Administration: Problems with the process and access to unapproved drugs
<p>Today, the vast majority of drugs available for patient use have gone through a rigorous system of human clinical trials supervised by the Food and Drug Administration (FDA), to ensure the drugs are safe and efficacious. There are now citizen advocacy groups that seek use of drugs not yet …
-
An Economic and Regulatory Analysis of Gene Therapy Products Authorized by the US Food and Drug Administration and the European Medicines Agency
… process of gene therapy products by the Food and Drug Administration (FDA) and the European Medicines Agency (EMA), evaluated the post-marketing safety signals reported to the FDA Adverse Event Reporting System (FAERS), and assessed the cost-effectiveness analysis of three gene therapies …
-
Environmental Fate of Ivermectin and its biological metabolites in Soils: Potential implications for the Environmental Impact of Ivermectin Mass Drug Administration for Malaria Control
… data suggests that most IVM-administered drugs remain intact, and more than 90 % of this drug is eliminated in feces. Biological metabolites: 3′′-O-demethylivermectin (3DI) and 24-hydroxymethyl ivermectin (24OHI) are also excreted in feces. Therefore, using manure from treated cattle as …
-
An Assessment of Deficits in Simple Discrimination Following Frontal Traumatic Brain Injury in Rats: The Relative Contribution of Motor Deficits, Motivation Deficits and Neuroprotective Drug Administration
… break points and low rates of responding. Administration of NAM reduced deficits in discrimination and PR performance. There were no gross motor deficits as a result of the injury. On the MWM task and measures of lesion size, there were no improvements due to NAM administration. Based on …
-
Absorption, Distribution and Excretion of Oxytetracycline and Tetracycline in Female Beagles
… female beagles following intra-arterial and oral drug administration. Concentrations of drug in body fluids and selected tissues were determined by high performance liquid chromatography utilizing an internal standard. The average biologic half-life of oxytetracycline was 6.4 hours, whereas that …
-
The vaccine and the virus: An autoethnographic account of HPV, sex education, and the psychosocial effects of STI's
<p>In 2006 the Food and Drug Administration (FDA) approved the Gardasil vaccine to assist in the protection from the Human Papillomavirus (HPV): The leading contributor to cervical cancer. After stressing the importance of the vaccine, but disregarding its inadequacies, young women were subjected …
-
Spinal cord implants for nerve regeneration
… the possible pathways through the Food and Drug Administration (FDA) and to the market.
-
ETHICAL CONSIDERATIONS OF THE USE OF INVESTIGATIONAL NEW DRUGS DURING THE GULF WAR
… of Defense to seek a waiver from the Food and Drug Administration to use the investigational new drugs pyridostigmine bromide and botulism vaccine without first obtaining consent from those servicemen and women who would receive the drugs. The waiver was granted and came in the form of the …
-
A description of practices of analgesia administration by advanced life support paramedics in the City of Cape Town
… descriptive survey was undertaken of analgesic drug administration by advanced life support (ALS) paramedics. Patient care records (PCRs) generated in t he City of Cape Town during an 11 month period containing administrations of Morphine, Ketamine, Nitrates and 50% Nitrous Oxide/Oxygen were …
-
The trouble with white pants: medicalisation and agency in the context of menstrual suppression
… the United States of America Food and Drug Administration approval of the first ECOC called Seasonale in 2003. Rather than framing ECOC as simply a forward trajectory of biomedical technologies, or as a medical 'take-over' of another aspect of women's bodies, it examines the ways in …
-
MANUFACTURE OF INDIVIDUALIZED DOSING: DEVELOPMENT AND CONTROL OF A DROPWISE ADDITIVE MANUFACTURING PROCESS FOR MELT BASED PHARMACEUTICAL PRODUCTS
… treatments. In recent years, the US Food and Drug Administration (FDA) introduced the Quality by Design (QbD) and Process Analytical Technology (PAT) guidelines to encourage innovation and efficiency in pharmaceutical development, manufacturing and quality assurance. As a result of emerging …
-
Optimization of Signal-Detection Methods in Novel Databases: a Focus on Direct-Acting Antivirals
An adverse drug event (ADE) is an injury resulting from medical intervention related to a drug, and they include medication errors, adverse drug reactions, allergic reactions, and overdoses. In 2019, the Food and Drug Administration (FDA) identified the following outcomes as potential signals of …
-
Comparative and population genomic analyses of the parasitic blood flukes
… control and ultimately elimination through mass-drug administration (MDA), reliant on the only available drug, praziquantel. In this thesis, I first present the results of the first genomic study investigating the potential impact of long-term mass-drug administration (MDA) on Schistosoma mansoni …
-
A mathematical modelling approach for the elimination of malaria in Mpumalanga, South Africa
… such as scaling-up vector control, mass drug administration, focal screen and treat campaign at the Mpumalanga-Maputo border-control point and source reduction are applied to the model to assess their potential impact on transmission and whether they may be used alone or in combination to …
-
Local drug delivery for treatment of brain tumor associated edema
… cause of morbidity from brain tumor. Systemic administration of corticosteroids, the standard of care, is highly effective but can introduce serious systemic complications. Agents that inhibit the vascular endothelial growth factor (VEGF) pathway, such as cediranib, are promising alternatives, …
-
Review of drug and biologics recalls: 2009 through 2019
<p>This study analyzed drugs and biologics recalls for the period of 2009 and 2019. The data used in the study was generated from Food and Drug Administration records. A total of 466 drugs and 84 biologics were recalled during the 11-year period. The common causes of drug product recalls included …
-
Toward understanding and mitigating heterogeneity in bone marrow stromal cell cultures for improved therapeutic efficacy
… as translational applications, and U.S. Food & Drug Administration approval for BMSC therapies has yet to be achieved for any of the several dozen indications explored to date.
-
Improvement of prescription medicine adherence through the development of an intelligent pill organization and dispensary system "Claire"
… of people who die each year due to accidental drug administration, the nation spends over $100 billion annually on health care costs directly related to incorrect medication adherence. Most medication non-adherence is caused by unintentional mistakes, especially among the elderly (65+ years …
Page 1 of 15