Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"droplet-based microfluidics"”.
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Droplet-Based Microfluidics for High-Throughput Single-Cell Omics Profiling
Droplet-based microfluidics is a powerful tool permitting massive-scale single-cell analysis in pico-/nano-liter water-in-oil droplets. It has been integrated into various library preparation techniques to accomplish high-throughput scRNA-seq, scDNA-seq, scATAC-seq, scChIP-seq, as well as …
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Tunable encapsulations: Droplet-based microfluidics for the expansion of biodegradable polymer technologies
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-14 without embargo terms
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Oscillating Dispersed-Phase Co-Flow Microfluidic Droplet Generation: Effects on Jet Length and Droplet Size
Droplet-based microfluidics have emerged as versatile platforms offering unique advantages in biology and chemistry. Although there is adequate control on size and monodispersity, most conventional microfluidic techniques cannot generate more than one droplet size at a time in a continuous and …
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An Experimental Investigation of Electrowetting Modulated Nucleate Boiling
… (EW) has drawn significant research interests in droplet-based microfluidics, and most applications focus on electronic displays, lab-on-a-chip devices and electro-optical switches, etc. In this work, we report a novel application of EW in enhancing nucleate boiling heat transfer. The working …
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Droplet IO : programmable droplets for human-material interaction
In this thesis, I propose aqueous droplets as a form of programmable material that can computationally transform its physical properties. Liquid matter can undergo physical transformation through interfacial forces and surface tension. I introduce a system called DropletIO to regulate interfacial …
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Ultrasensitive methods for the detection of biomolecular systems at the micro/nano scale
… In particular, the combined use of a droplet-based microfluidics, PNA-MBs and fluorescence microscopy enabled the selective and sensitive detection of DNA in an innovative and efficient platform. The experiments were carried out by using both oligonucleotides and PCR amplification …
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Influencing contact-line behavior in dynamic wetting through thermocapillarity and surface topography
… be seen in day-to-day occurrences such as water droplets sliding on a glass window on a rainy day, where the droplet displaces the air surrounding the glass surface as it slides, and in industrial processes such as slot-die coating, where the coating liquid displaces the surrounding air to coat a …
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Biophysical approaches to single-cell characterization
… scRNA-seq data. Tissues are divided into layers based on the accessibility of a fluorescent dye allowing sorted cells to be characterized by transcriptomic and regional identity. I use SEEP to explore how the transcriptional states of cells in high-grade serous ovarian cancer vary with respect to …
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Low-Input and Single-Cell Transcriptomic Technologies and Their Application to Disease Studies
… higher than full-length methods. We developed a droplet-based platform for full-length single-cell RNA-seq, which enabled the efficient recovery of full-length mRNA from individual cells in a high-throughput manner. The developed platform can process ~8,000 single cells within 2 days and detect …