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Showing 1 to 2 of 2 for “"double Holliday Junction"”.

  1. The Role of Esc2 and DNA in Smc5/6-mediated Sgs1-Top3-Rmi1 Sumoylation

    … by many obstacles or damages such as DNA double-strand breaks (DSBs). There are several mechanisms to deal with DSBs and replication blockages, including homologous recombination (HR). HR leads to the formation of DNA intermediates such as Holliday junctions (HJ), which are processed by …

    texas-state Repository record for The Role of Esc2 and DNA in Smc5/6-mediated Sgs1-Top3-Rmi1 Sumoylation (opens in a new tab)

  2. Genetic Analysis of Crossover Defective Mouse Spermatocytes Reveals Discrete Crossover Precursor Intermediates

    … cells, through a reductional division that doubles the number of cells, but not the number of chromosomes.</p> <p>Abnormal numbers of chromosomes, result in aneuploidy. In humans, 1-8% of spermatocytes and 10-30% of oocytes are aneuploid, contributing to ~ 5% of clinically detected …

    uthsc Repository record for Genetic Analysis of Crossover Defective Mouse Spermatocytes Reveals Discrete Crossover Precursor Intermediates (opens in a new tab)