Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"dose-ranging study"”.
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DOSE RANGING STUDY OF LUTEIN SUPPLEMENTATION IN ELDERLY WITH AND WITHOUT AGE RELATED MACULAR DEGENERATION
… act as optical filters. The objectives of this study were to investigate the association between three doses of orally ingested lutein supplements and serum levels of this carotenoid in elderly with and without AMD; to evaluate the possible interaction between supplemental lutein and other …
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Enhancing the use of opioids in pain management: antinociceptive potentiation with opioid agonist/antagonist combinations.
… of an opioid agonist and "ultra-low" (nanomole) doses of an opioid antagonist. A recent animal study reported that antinociception may be significantly enhanced with the combination of the partial opioid agonist/antagonist buprenorphine and ultra-low doses of the antagonist naloxone. The central …
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Innovative Methods for the Design and Analysis of Phase II Clinical Trials
… key challenges in phase II trials in terms of dose-ranging study, patient population selection, and decentralized clinical trials (DCTs). This dissertation presents a comprehensive set of methodologies that address these critical issues with three projects. The first project introduces a …