Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"dose reconstruction"”.
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4D Monte Carlo Based Patient Dose Reconstruction Incorporating Surface Motion Measurements
… assess the impact of respiratory motion on the dose delivered during radiotherapy using a previously validated 4D Monte Carlo-based dose reconstruction tool, 4Ddefdosxyznrc. As a surrogate for tumour motion, abdominal surface motion measurements were recorded during patient treatments using the …
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Advancement of A 3D Computational Phantom and Its Age Scaling Methodologies For Retrospective Dose Reconstruction Studies
… phantom for over two decades for retrospective dose reconstruction studies of childhood cancer survivors (CCS) treated with 2D historic radiotherapy (RT). However, our phantom and its age scaling functions (ASF) must be updated so that it can be used in studies that include survivors treated …
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Infrastructure Development For Personalized Risk Prediction to Reduce Cardiovascular Disease In Childhood Cancer Survivors
… and this risk rises with higher mean heart doses and increased RT exposure to larger cardiac volumes. Since, the heart is a heterogeneous organ made up of several distinct substructures, RT dose received by the entire heart does not accurately represent the doses to the various cardiac …
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Risk and Risk Factors For Colorectal Subsequent Malignancies In Survivors of Childhood Cancer: A Report From The Childhood Cancer Survivor Study
… therapy (RT) data – colorectal and substructure dose-volume metrics – as risk factors for colorectal SMN risk; metrics that have yet to be thoroughly investigated. We developed a novel population-based anatomical colorectal model with substructures for RT dosimetry in late effects studies of …
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Applications of Statistical Modeling in Iterative CT Image Reconstruction
… an analytical solution to the idealized CT image reconstruction problem, the inverse problem of turning raw x-ray measurements into a full 3-dimensional (3D) image, and is derived assuming a continuous set of noiseless measurements. However real CT data are noisy and biased, especially so if the …
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The Role of Cell Sterilization In Population Based Studies of Radiogenic Second Cancers Following Radiation Therapy
… relevant quantity, cancer equivalent dose (<em>D</em><sub>CE</sub>), to estimate risk instead of mean absorbed dose (<em>D</em><sub>MA</sub>). Our objective was to demonstrate that when <em>D</em><sub>CE</sub> is used fewer subjects are needed for clinical trials. Thus, we compared the …
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Radiation Dose Estimation for Pediatric Patients Undergoing Cardiac Catheterization
… in modern imaging systems with automatic dose rate modulation. </p><p>The overall objective of this dissertation was to develop a comprehensive method of radiation dose estimation for pediatric patients undergoing cardiac catheterization. In this dissertation, the research is divided into …
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Data-driven X-ray Tomographic Imaging and Applications to 4D Material Characterization
… as measurements with insufficient dosage (low-dose) and measurements with insufficient projection angles (sparse-view), have been proposed to relieve these problems but are generally compromising imaging quality. Such a dilemma inspires the development of advanced tomographic imaging …
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Adaptive Radiation Therapy Of Prostate Cancer
… before the treatment and takes into account dose delivery variation daily to compensate for the difference between planned and delivered dose. It also has potential to allow further dose escalation and margin reduction to improve the clinical outcome. This retrospective study evaluated ART …