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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 115 for “"dose rate"”.

  1. Continuous low dose rate irradiation of the rat brain

    Madhoo, JiteshDivision of Radiation Oncology1999

    … may be achieved with the use of continuous low dose rate external beam radiotherapy, where the treatment is administered over a 12 to 24 hour period. A relationship between fractionated and continuous low dose rate irradiation has been reported for skin, however, no such relationship has been …

    cape-town Repository record

  2. Automated Treatment Planning in High Dose-Rate Brachytherapy for Cervical Cancer

    Gonzalez, Yesenia Amanda2023

    … by a boost to the cervix tumor site with High-dose-rate brachytherapy (HDRBT). HDRBT is a procedure that involves the insertion of radioactive sources into the tumorous area to ablate the cancer. Treatment planning for the procedure is typically performed on the day of treatment. The complex …

    utswmed Repository record

  3. Irradiators for measuring the biological effects of low dose-rate ionizing radiation fields

    Davidson, Matthew AllenMassachusetts Institute of Technology2011

    … field. Particle type, energy spectrum, and dose-rate all affect biological response per unit dose. This thesis describes methods of spectral analysis, dosimetry, biological assays, and mathematical modeling for determining the relative biological response for low dose-rate fields. The …

    mit Repository record

  4. Predictive modelling of external dose rate from radionuclide therapy patients following discharge from hospital

    University of Malta2015

    … attempts were made to predict the external dose rate, however, there is a lack of accuracy in predictions from existing models of dose rate decay. Objectives: Published models were compared to actual patient measurements to test their validity. A patient speci c model was developed to …

    malta Repository record

  5. RADIATION-INDUCED CHROMOSOME INSTABILITY AND INTERCELLULAR COMMUNICATION: THE ROLE OF DOSE RATE AND IMPLICATIONS FOR CARCINOGENESIS

    Elbakrawy, Eman Mohammed AhmedOxford Brookes University2017

    The biological risks associated with low dose and low dose rate (LDR) radiation exposures are not yet well characterised. Experimental studies indicate that in addition to biological effects resulting from direct DNA damage, a variety of non-DNA targeted effects (NTE) including radiation-induced …

    oxford-brookes Repository record

  6. Effect of dose and dose rate on benzo[a]pyrene induced mutational spectra in human cells

    Chen, JiaMassachusetts Institute of Technology1994

    Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Civil Engineering, 1994.

    mit Repository record

  7. Dose-rate-effects in XRCC1 wild-type and mutant CHO cell lines using An ²⁴¹AM source

    Chambers, Dwight McCoyMassachusetts Institute of Technology2008

    This work explores the effects of low-dose-rate radiation on both the AA8 (wild-type CHO cells) and EM9 (XRCC1 null CHO mutants) cell lines. In particular, this study performed clonogenic survival and growth assays to determine the radiations/ effect on the cells proliferative capacity. It was …

    mit Repository record

  8. The effect of high dose rate on tissue equivalent proportional counter measurements in mixed neutron-gamma fields

    Qashua, NaelUniversity of Ontario Institute of Technology2010

    … power plants. In such radiation fields, the dose rate of each component can vary drastically from extremely low to very high. Among these possible combinations of radiation fields with very different dose rates, a mixed field of an intense photon and a weak neutron dose component is the more …

    uoit Repository record

  9. Preliminary investigation of a possible dose rate effect on survival of cells irradiated with low energy protons

    Robinson, L P GDepartment of Physics1989

    … work was to investigate and measure a possible dose rate effect on the survival of V79 cells, in the dose range from zero to 25 Gy, at dose rates of about 3 Gy/s and 300 Gy/s. The survival curves initially obtained were anomalous in that they showed abnormally high levels of survival and a …

    cape-town Repository record

  10. Shutdown Dose Rate Modeling for Radiation Requirements Development and Design Trend Analysis in the ARC Fusion Device

    Murphy, Daniel T.Massachusetts Institute of Technology2024

    … components. Designing robotic systems to operate in this radiation environment requires understanding the expected radiation levels and how design decisions impact those levels. This thesis uses the Rigorous Two-Step (R2S) methodology to scope the radiation environment and provide data for …

    mit Repository record

  11. Application and Development of Algebraic Reconstruction Algorithms for High Dose Rate Brachytherapy Gel Dosimetry with Optical Computed Tomography Readout

    DeVries, David2018

    … as patient specific quality assurance. High dose rate (HDR) brachytherapy treatments have become more complex, but patient specific QA has not been adopted. One reason for this is the lack of inexpensive, simple to use, accurate, and complete dosimeters for brachytherapy. Radiochromic gel …

    queens Repository record

  12. Characterization of the Neutron Irradiation System for use in the Low-Dose-Rate Irradiation Facility at Sandia National Laboratories

    Franco, Jr. Manuel

    … use at Sandia National Laboratories (SNL) Low Dose Rate Irradiation Facility (LDRIF). With a total activity of 0.3 TBq (9 Ci), the source consisted of three recycled 241AmBe sources of different activities that had been combined into a single source. The source in its polyethylene shielding …

    unm Repository record

  13. Development and Implementation of A Remote Audit to ol For High Dose Rate (Hdr) 192Ir Brachytherapy Using Optically Stimulated Luminescence Dosimetry

    Casey, Kevin2012

    … determine correction factors for linearity with dose, dose rate, and the combined effect of irradiation energy and phantom construction. The uncertainties introduced by source positioning in the phantom and timer resolution limitations were also investigated. It was found that the linearity …

    uthsc Repository record

  14. Fast Monte Carlo Cell-By-Cell Simulation of Radiation-Induced DNA Damage, Chromosome Aberrations, and Cell Death for Low-Dose-Rate Brachytherapy Sources

    Dick, Joseph S.Georgia Institute of Technology2025

    … viable using the corresponding SDD file generated by TOPAS-nBio. Rather than utilizing the computationally intensive TOPAS-nBio to produce the SDD file for each exposure scenario and for each cell, code was developed to rapidly generate SDD files based on pre-computed single-electron-track …

    gatech Repository record

  15. Pre-clinical evaluation of lethal and sublethal DNA damage in human cell cultures by ultrashort pulse and ultra-high dose rate laser accelerated protons

    Maiorino, CarlaQueen's University Belfast2021

    … brain and heart. Numerous studies have demonstrated the feasibility of using high LET particles in tumor cells; however, the very high installation and operational costs limit the utilization of particle therapy.<br/><br/>The idea of future facilities based on laser-driven ion accelerators has …

    qu-belfast Repository record

  16. The rate of decay of fresh fission products from a nuclear reactor

    Dolan, David J., author, Johnson, Thomas, advisor, Brandl, Alexander, committee member, Desir, Rosemond, committee memberColorado State University. Libraries2013

    Determining the rate of decay of fresh fission products from a nuclear reactor is complex because of the number of isotopes involved, different types of decay, half-lives of the isotopes, and some isotopes decay into other radioactive isotopes. Traditionally, a simplified rule of t-1.2 or 7s and …

    colostate Repository record

  17. Beam characterization for accelerator-based boron neutron capture therapy using the ⁹Be(d,n) nuclear reaction

    White, Susan Marie, 1973-Massachusetts Institute of Technology1998

    … therapies (AB-BNCT) was investigated. The moderated neutron spectra produced at several deuteron bombarding energies were evaluated in terms of dose rates and dosimetric profiles in a water-filled brain phantom using an existing heavy water moderator and lead reflector assembly. Dosimetry …

    mit Repository record

  18. An evaluation of the natural radioactivity in the soils of Okahandja and Karibib, Namibia

    Midzi, WilfredUniversity of Namibia2018

    … were used to calculate the absorbed dose rates and effective dose rates in air in the two towns. The average absorbed dose rate in air in Okahandja is 77.3 ± 18.0 nGy/hr while that in Karibib is 77.6 ± 10.9 nGy/hr. However, the resulting average effective dose rate in Okahandja and …

    namibia Repository record

  19. Facilitating the Clinical Translation of Flash Radiotherapy Through Dosimetry Development and Beam Parameter Optimization

    Liu, Kevin, <p>https://orcid.org/0000-0002-0942-6513</p>2025

    … complications<sup>1</sup>. Recently, ultra-high dose-rate (UHDR) RT (mean dose rates ≥40 Gy/s for a total duration of ≤200 ms) has been reported to selectively spare normal tissues and organs while maintaining an isoeffective tumoricidal effect compared to conventional (CONV) dose rate RT in a …

    uthsc Repository record

  20. Advanced brachytherapy dosimetric considerations

    Melhus, Christopher S. (Christopher Scott), 1974-Massachusetts Institute of Technology2008

    … was investigated with emphasis on evaluations of dose distributions and shielding considerations for both photon- and neutron-emitting radionuclides. Monte Carlo simulation methods were employed to calculate dose distributions for virtual and commercial brachytherapy sources. Radionuclides studied …

    mit Repository record

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