Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"dose accumulation"”.
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Development of Advanced Mr-Guided Adaptive Radiation Therapy Methods For Head & Neck Cancers On The 1.5T Mr-Linac
… potential for advanced ART strategies such as dose-optimized ART, in which the treatment plan is optimized based on the accumulated dose over previous fractions, or biological image-guided ART, in which the plan is adapted based on individual tumor response as measured through quantitative …
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Improving Dose-Response Correlations For Locally Advanced Nsclc Patients Treated With Imrt Or Pspt
… patients remains below 28 months. Higher tumor dose has been found to increase survival but also a higher rate of radiation pneumonitis (RP) that affects breathing capability. In fear of such toxicity, less-aggressive treatment plans are often clinically preferred, leading to metastasis and …
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Motion Estimation and Motion-Compensated Reconstruction for Four-Dimensional Cone Beam Computed Tomography (4D-CBCT)
… radiation therapy (SBRT) characterizing as high dose in each fraction and few fraction number requires higher accuracy for tumor localization. For organs influenced by the respiration, respiration induced motion becomes the principal cause for tumor localization uncertainty and four dimensional …
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Accumulating delivered dose to the rectum to improve toxicity prediction in prostate radiotherapy
Accumulating delivered dose to the rectum to improve toxicity prediction in prostate radiotherapy Leila E. A. Shelley Gastrointestinal (GI) toxicity is a clinical issue suffered by up to 22% of prostate cancer radiotherapy patients. However, the relationship between radiation dose and toxicity is …
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Optimization of Lead Spectinamide Compounds as Novel Anti-tuberculosis Agents with a Pharmacometric Approach
… epidermis and other surface tissue. In multiple-dose accumulation studies, the Cmax of radiolabeled compound after the 1st dose and the 8th dose of twice-daily dosing regimen was similar: 3.39µCi/mL and 3.55µCi/mL, suggesting no relevant accumulation of parent drug and metabolites. The …
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Optimization of Image Guided Radiation Therapy for Lung Cancer Using Limited-angle Projections
… acquisition enables scan time and imaging dose reduction and improves the mechanical clearance of imaging.</p><p>First of all, the dissertation developed a phase-matched digital tomosynthesis (DTS) technique using limited-angle (<=30 deg) projections for lung tumor localization. This …