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Showing 1 to 20 of 920 for “"dosage"”.
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The interactive effect of depressant type and dosage with frother dosage in the flotation of a PGE ore
… gangue in the concentrates. Depending on dosage, depressants may also affect the recovery of the valuable minerals in the ore positively by slime cleaning or negatively by depression. Depression of stabilising gangue minerals such as talc decreases the froth stability and may also affect …
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Targeting Telomerase Overexpression by Synthetic Dosage Lethality
… Genetic interactions, such as synthetic dosage lethality can overcome these issues and identify targets that is specific only tumor cells that overexpress telomerase. We used a combination of pooled shRNA and CRISPR screening platforms to comprehensively query the entire human genome and …
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Writing Therapy Benefits May Be Dosage Dependent
This study investigated whether there was a dosage effect for the benefits of writing therapy, specifically writing about one's best possible future self. The primary hypothesis was that writing about one's best possible future self twenty minutes per day for four days (high dosage) would result in …
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Versatility of hot-melt extrusion for dosage form design
… as a technique for manufacturing a variety of dosage forms. In this research, HME was applied in different ways to achieve different goals, such as solubility enhancement, taste masking, solid state stability enhancement, and sustained release formulations for oral drug delivery, using one …
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The role of dosage sensitive genes in aneuploid phenotypes
… Our results indicate that subtle changes in gene dosage across a chromosome can have significant phenotypic consequences. We conclude that phenotypic thresholds can be crossed by mass action of copy number changes that on their own are benign.
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Formulation of oral dosage forms by three dimensional printing
… of fast-release and extended-release oral dosage forms. Tablets were processed by employing a method of solid freeform fabrication known as three dimensional printingTM (3DPTM). A microcrystalline cellulose powder was used in combination with pH-dependent and permeable polymeric binder …
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The measurement of beta radiation dosage with photographic emulsions
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Physics, 1951.
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Esx1 Dosage Impacts Reproductive Fitness: Effects On Viability and Fertility
… suggesting tight control of X-chromosome gene dosage is important for reproduction. Esx1 is a mouse homeobox gene on the X-chromosome with expression limited to extraembryonic tissues and testicular germ cells. Here, we examine the effects of increased and decreased Esx1 dosage on placental and …
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Novel Carbopol-Wax Blends for Controlled Release Oral Dosage Forms
<p>Carbopol is crosslinked acrylic acid. Carbopol can be used in developing formulations for transdermal, oral, rectal use. It is forms strong gel in low concentration. Therefore, it can be used in low concentration in developing controlled release formulations. This increases the cost …
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Fused deposition modelling three-dimensional printing of solid dosage forms
… for the design and manufacture of complex solid dosage forms with the objective of formulating personalized medicines and on-demand manufacturing. Among commercially available models, fused deposition modelling 3D-printing (FDM-3DP) has shown the potential to fabricate objects with various …
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Design of novel drug delivery system and optimal dosage regimens
Three representative drug delivery systems were analyzed to emphasize the roles of mathematical models and computer-aided simulations in pharmaceutical research. In the first project, a protocol was developed so that the optimal regimen, consisting of the intravenous boluses and subsequent infusion …
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Identifying Dosage Effect of LEDT on Muscular Fatigue in Quadriceps
… this study was to compare the effects of various dosages of light emitting diode therapy (LEDT) on muscle fatigue, while performing a single leg extension to exhaustion. 34 recreationally resistance trained athletes between the ages of 18 and 26 participated in four trials. Each trial included pre …
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DEVELOPMENT OF A NEW CONTROLLED RELEASE DOSAGE FORM OF ACETYLSALICYLIC ACID
… both an enteric-coated and controlled release dosage form. Acetylsalicylic acid granules were microencapsulated in the laboratory, using Eudragit L30D (an aqueous based enteric coating resin) and a fluidized bed coating apparatus. Portions of the microencapsulated granules were compressed into …
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Targeting the dosage compensation complex to the chromosome in Drosophila melanogaster
Contains fulltext : 65589_targthdoc.pdf (Publisher’s version ) (Open Access) Contains fulltext : 72554.pdf (Publisher’s version ) (Open Access)
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Critical Quality Attributes of Topical Semi-solid Dosage Forms: Solvent Activity
… critical quality attribute of topical semi-solid dosage forms. Primary goal of this study was to investigate the mechanistic effects of water activity on drug release properties of formulation and drug permeation across the skin. A related objective was to investigate the mechanistic effects of …
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Improvement of Release Criteria for Immediate Release Solid Oral Dosage Forms
Herewith are presented the results of an investigation the statistical power of USP compendial release tests and recommended alternatives.</p><p> The U.S. drug supply chain, formerly protected by a closed distribution network, is now threatened by the legal and illegal importation of drug products. …
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Oral dosage form modifications for older adults: a mixed methods investigation
Introduction: Oral dosage forms (ODFs), particularly solid ODFs, are the most popular and most commonly prescribed of all medication formulations. Older adults are the highest consumers of prescription medication. However, age-related pharmacokinetic, pharmacodynamic and physiological changes can …
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Dosage Effects of Methylphenidate on the Activity Level of Hyperactive Children
Made available in DSpace on 2014-12-12T01:12:11Z (GMT). No. of bitstreams: 1 7212442.pdf: 4126874 bytes, checksum: 3fed8fbbc25f8755930c97733e2657ca (MD5) Previous issue date: 1971
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The design and manufacture of immediate-release optimal solid dosage forms
… pharmaceutical products, immediate-release solid dosage forms, from drug substance and excipient are: blending, wet granulating, drying, milling and screening, blending, tableting, coating, and so on. A new process, such as blending combined with solvent-less, multi-component injection-molding …
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