Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 85 for “"dorsolateral prefrontal cortex"”.
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A non-human primate model of dorsolateral prefrontal cortex dysfunction in schizophrenia
… neural circuits supporting SWM, principally the dorsolateral prefrontal cortex (dlPFC). One of these changes in schizophrenia is a loss of perineuronal nets (PNNs), extracellular matrix structures that serve to protect and support the function of neurons, within the dlPFC (Mauney et al., 2013). …
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Transcranial Direct Current Stimulation of the Dorsolateral Prefrontal Cortex Does Not Improve Handgrip Time-to-Failure or Alter Central or Peripheral Hemodynamics
… study was to determine if tDCS delivered to the dorsolateral prefrontal cortex (DLPFC) would improve handgrip time-to-failure in adults 60 years old and older. Twenty-five participants completed five maximal voluntary contractions, followed by 20-minutes of a-tDCS or SHAM conditions. Next, …
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The role of ventromedial and dorsolateral prefrontal cortex in physiological and behavioural dysfunction in non-human primates, of relevance to mood and anxiety disorders
… of area 25 of the subcallosal anterior cingulate cortex and area 46 of the dorsolateral prefrontal (dlPFC) cortex in depression- and anxiety-like behaviour in a non-human primate, the common marmoset. Depressed patients show hyperactivity in area 25, and hyperactivity and hypoactivity of area 46 …
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Dreaming and the dorsolateral frontal lobes : towards a better understanding of the mechanism of dreaming
… Based on exploratory findings that damage to the dorsolateral prefrontal cortex does not cause changes in these patients subjective experience of their dreams (Solms, 1997), a study was conducted in order to investigate the role of this area in dream production. The dreams of seven patients with …
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Unique and shared roles of the prefrontal and posterior parietal cortex in cognitive functions
The dorsolateral prefrontal cortex and the posterior parietal cortex are parts of the cortical network involved in attention, working-memory and executive function. The two areas share a number of similarities, although functional differences between the two have also been identified. A widely …
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COMT Genotype, Schizophrenia, and Dopamine Transmission
… for dopamine signal deactivation in the dorsolateral prefrontal cortex, an area of the brain associated with working memory. Working memory deficits are found in persons with schizophrenia and their unaffected siblings. A single nucleotide polymorphism of the COMT gene results in a …
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Attentional Uncertainty in the Stroop Priming Task
… in the anterior attentional system (i.e. dorsolateral prefrontal cortex and anterior cingulate) are susceptible to normal aging processes, whereas structural changes in the posterior attentional system are minimal. Using the Stroop priming task, we investigated whether reducing the …
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Cognitive Performance as A Function of Right-Sided, Low-Frequency rTMS Administration Using CNS Vital Signs
… approach that stimulates the cerebral cortex, as an alternative to ECT has become a major research focus. The efficacy of both high-frequency and low-frequency rTMS for depression have been well documented although the impact on neurocognitive functioning is not completely understood. …
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Emotion, Depression, and Asymmetric Brain Function
… with abnormal functional asymmetries in frontal cortex, functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) studies have largely failed to identify specific brain regions showing this effect. This failure likely stems in part from the widespread use of …
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Triggering and measuring neural response indicative of inhibition in humans during conversations with virtual humans
… virtual human can evoke a response in the prefrontal cortex, indicative of inhibiting an antisocial response. It follows previous studies by Aleksandra Landowska (2018) and Schilbach (2016) demonstrating that a prefrontal cortex response indicative of inhibition can be evoked by a virtual …
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Investigating neuroinflammation in schizophrenia: a proton magnetic resonance spectroscopy (1H-MRS) and cytokine study
… with voxels located in the anterior cingulate cortex (ACC) and left thalamus as well as a chemical-shift imaging 2-dimensional slice. Neurometabolites obtained included glutamatergic metabolites (glutamate (Glu), glutamine (Gln) and glutamate plus glutamine (Glx)) and neuroinflammatory …
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Variability of Neural Responses in the Lateral Prefrontal Cortex
… period in which the stimulus is absent. The dorsolateral prefrontal cortex has long been implicated as the seat of visuospatial working memory, and undergoes dramatic increases in volume and functional connectivity during and around the time of puberty. However, much of the neurophysiological …
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Electrocorticographic Neural Correlates of Arm Movements and Associated Goal Orientation in Humans
… direction, position and speed throughout the cortex. In particular, velocity tuning was best represented spectrally in a high gamma band from around 90-150 Hz in the primary motor cortical regions. In dorsolateral prefrontal cortex: DLPFC), cortical activity in the 150-250 Hz band of the ECoG …
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Exploration of the influence of emotionally primed environments on creativity and related patterns of brain activity
… analysis suggested that the brain regions of the dorsolateral prefrontal cortex (DLPFC), anterior cingulate gyrus (ACC), and anterior insula are active under both stimuli associated with increased divergent thinking. Future work is needed to investigate specifically how these brain regions may …
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Resting-State Functional Brain Networks in Bipolar Spectrum Disorder: A Graph Theoretical Investigation
… characteristic of BSD stems from disrupted prefrontal control over subcortical limbic structures (Strakowski et al., 2012; Depue & Iacono, 1989). However, existing neuroimaging research on functional connectivity between frontal and limbic brain regions remains inconclusive, and is unable to …
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PTSD Symptom Severity and Neurocognitive Performance as a Function of Combined TMS and Imaginal Exposure in OIF/OEF Combat Veterans with Treatment Resistant PTSD
… magnetic stimulation (TMS) to the right dorsolateral prefrontal cortex (DLPFC) and the supplementary motor area (SMA) with a standardized exposure protocol for the treatment of chronic, treatment-resistant PTSD. The aims are to (1) determine if the treatment is safe and well tolerated, …
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Social Cognition in Disorders of the Basal Ganglia
… disordered activity in the circuitry linking the dorsolateral prefrontal cortex and the basal ganglia. Patients with Huntington’s exhibited reduced fear responses which most likely results from abnormal amygdala activity. Patients with Tourette’s exhibited deficits on a wide range of social …
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PERSISTENT ACTIVITY DURING WORKING MEMORY: MATURATION AND CORTICAL SPECIALIZATION
… one of the most critical cognitive functions and dorsolateral prefrontal cortex (dlPFC) has generally been recognized as the seat of working memory. Development of working memory ability through adolescence, accompanied by structural changes has been reported in human studies, however, how …
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Neural Dysfunction during Decision-Making as a Predictor of Cocaine Relapse
… in the precuneus, bilateral orbitofrontal cortex, left insula, right dorsolateral prefrontal cortex, paracingulate, left hippocampus, and bilateral amygdala correctly classified 71% of patients by short-term and long-term relapse. This investigation suggests that neuroimaging may be a valid …
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Cognitive Control as a Function of Anger Expression Style: A Combined ERP and fMRI Investigation
… that anger-out was associated with greater left dorsolateral prefrontal cortex (DLPFC) activity than anger-in, evidence in support of the motivational model of emotion. Contrary to hypotheses, anger-out was not linked to cognitive control impairment. However, consistent with hypotheses, anger-in …
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