Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"dorsal closure"”.
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Understanding the Organization, Location, and Interactions of Actin-based Structures During Drosophila Dorsal Closure
… I used live, 4D imaging to observe Drosophila dorsal closure, a model of epithelial sheet morphogenesis. I compared four fluorescently tagged F-actin probes widely used by Drosophila researchers to determine which was optimal for imaging dorsal closure. I observed differences in the intensity …
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Roles of the Chromatin Insulator Protein Cp190 in the Development of Drosophila melanogaster
… development by affecting nuclear migration or dorsal closure, two myosindependent events. To explore this supposition, embryos lacking maternal contribution and homozygous for the Cp190 mutation (deleted C-terminus) were stained in order to view nuclear migration and to determine their …
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Analysis of the role of Drosophila IMP in actin mRNA localization and cell migration
… not complete embryogenesis and fail to undergo dorsal closure. One of the working models for IMP function is that it localizes actin mRNA to the leading edge of migrating cells. mRNA in situ for the two cytoplasmic actins in Drosophila (actin42A and actin5C) shows that both are localized to the …
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Genetic Approaches to Study Tissue Morphogenesis in Drosophila
… head segments during head involution, and the dorsal most row of epidermal (DME) cells during dorsal closure. These represent tissues that are undergoing extensive cell shape change or cell rearrangements. Sqh2P is localized very apically in these cells, and is noticeably enriched in filopodia …
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The Role of Zasp52 in the Morphogenesis of the Drosophila melanogaster Embryo
… of the supracellular actomyosin structure during dorsal closure. I now show that Zasp52 possesses a potential actin binding motif related to the one found in capping protein/CapZ across metazoans, and this motif is sufficient to bind actin in vitro. Zasp52’s in vivo localisation to actomyosin …
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Klonierung und funktionelle Analyse des Aktinreorganisators p150-Spir
… führt zum sogenannten dorsal closure-Phänotyp der Embryonen mit fehlender Zellstreckung und fehlender Migration dorsaler Epithelzellen. Der molekulare Mechanismus, mit dessen Hilfe Rho-GTPasen Aktinstrukturen regu-lieren und wie JNK Einfluss auf Zellmorphologie und …