Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"dopamine transport"”.
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Structural Determinants for Substrate and Inhibitor Recognition by the Dopamine Transporter
… holds that cocaine inhibits DAT-mediated dopamine transport via competition with dopamine for formation of an ionic bond with the DAT transmembrane 1 aspartic acid residue 79. A recent study from our laboratory indicated that mutation of this aspartate to glutamate (D79E) had little or no …
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A study of the neurotoxicity of MPTP and analogs in human neuroblastoma SH-SY5Y cells
… SH-SYS5Y human neuroblastoma cells through a non-dopamine transport mechanism, and was metabolized to 1-methyl-4-phenyl-2,3-dihydropyridium (MPDP⁺) and 1-methyl-4-phenylpyridium (MPP⁺) by monoamine oxidase (MAO). MPP⁺, the neurotoxic analog of MPTP, was taken up into cells through a dopamine (DA) …
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Dietary Plant Lectins May be an ‘Unknown Etiology’ in Parkinson’s Disease and Dietary Bioactive Compounds Affect Lifespan and Fat Storage Aspects of Caenorhabditis Elegans
… botulinum or ricin can trans-synaptically transport in nervous system. Our hypothesis 1: dietary plant lectins might be responsible for the “unknown pathogen” causing PD. Pomegranate juice (PJ) have antioxidant and anti-obesity effects. Our hypothesis 2: PJ increases lifespan in C. elegans …
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Insecticide-Mediated Neurochemical and Behavioral Changes as Possible Predisposing Environmental Factors in Idiopathic Parkinson's Disease
… with reduced levels of the neurotransmitter, dopamine. Behavioral and neurochemical analyses in C57BL6 mice were performed following a subchronic dosing regime with the organochlorine insecticide heptachlor or the pyrethroid deltamethrin. Results were compared to those induced by the …