Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"domoic acid"”.
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Understanding the Fate of the Neurotoxin Domoic Acid In Coastal Systems
<p>The elderly club program (ECP), a community-based intervention, has been implemented to support self-help organizations and promote the health and quality of life of seniors in Thailand. Due to dramatic increases in aging populations, it is important to determine whether or not the club …
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Neurological Effects of Low-Level, Chronic Domoic Acid Exposure in a Nonhuman Primate Model
… health risks to human and wildlife populations. Domoic acid (DA), the focus of this dissertation, is produced by algae in the genus Pseudo-nitzschia. DA is a potent glutamate receptor agonist and neurotoxin, and high-dose exposure to this toxin has been associated with severe illness and …
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Assessing the impact of domoic acid exposure on the zebrafish (Danio rerio) brain across life stages
Domoic acid (DA) is a neurotoxin produced by diatoms in genus Pseudo-nitzschia. DA accumulates in seafood and can affect the health of humans and wildlife. DA is a structural analog of glutamate - an excitatory neurotransmitter - that activates ionotropic glutamate receptors leading to …
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Impacts of developmental exposures to the harmful algal bloom toxin domoic acid on neural development and behavior
… affect human health. One HAB toxin of concern is domoic acid (DomA), a glutamate analog produced by the marine diatom Pseudo-nitzschia spp. Current regulatory limits are designed to prevent acute neurotoxicity in adult humans. However, research shows that low-level exposure during early life can …
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Impacts of developmental exposures to the harmful algal bloom toxin domoic acid on neural development and behavior
… affect human health. One HAB toxin of concern is domoic acid (DomA), a glutamate analog produced by the marine diatom Pseudo-nitzschia spp. Current regulatory limits are designed to prevent acute neurotoxicity in adult humans. However, research shows that low-level exposure during early life can …
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Asymmetric Allylation of Aldehydes Catalyzed by Formamide Organocatalysts. Studies Towards The Synthesis of L- Domoic Acid Side Chain
… of aldehydes. Classically metal-based Lewis acids are frequently used to catalyze this process. These Lewis acids are inherently sensitive to air and moisture and thus require strictly anhydrous reaction conditions. Recent developments in the field of catalysis have found chiral organic Lewis …
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Development of smartphone hyphenated colorimetric, plasmonic and electrochemical biosensors for food contaminant detection
… for the detection of a regulated marine toxin (domoic acid) in shellfish. This target is chosen since shellfish are produced in remote locations and toxin occurrence is increasing due to climate change. The first two chapters of the thesis critically analyse the state-of-the-art in screening and …
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Gene discovery and expression profiling in the toxin-producing marine diatom, Pseudo-nitzschia multiseries (Hasle) Hasle
… (Hasle) Hasle, produces the neurotoxin domoic acid, which is the cause of amnesic shellfish poisoning. The molecular characterization of this organism has been limited to date. Therefore, the focus of this thesis was to identify and initiate characterization of actively expressed genes …
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Gene discovery and expression profilng in the toxin-producing marine diatom, Pseudo-nitzschia multiseries (Hasle) Hasle
… (Hasle) Hasle, produces the the neurotoxin domoic acid, which is the cause of amnesic shellfish poisoning. The molecular characterization of this organism has been limited to date. Therefore, the focus of this thesis was to identify and initiate characterization of actively expressed genes …
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Insights Into Particulate Phosphorus Dynamics and toxic Algal Bloom Events From A 13-Year Sediment Trap Study In Santa Barbara Basin (CA)
… which can produce the neurotoxin domoic acid (DA) and has been responsible for numerous marine mammal and bird mortalities on the West Coast of the U.S. The goal of this dissertation is to examine particulate P cycling, Pseudo-nitzschia blooms, and DA export using a 13-year record …
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Factors that impact Pseudo-nitzschia spp. occurrence, growth, and toxin production
… (L4) and the environmental factors impacting on domoic acid (DA) production in these waters. This is combined with laboratory studies examining key environmental factors and the multifactorial impact of multiple macronutrient and micronutrient availability on PN growth and DA production. An LC-MS …
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Cloning and characterization of a novel ferritin from the marine diatom Pseudo-nitzschia multiseries
… waters, and are known to produce the neurotoxin domoic acid. Until now, the reason for the success of pennate diatoms in the open ocean was uncertain; however, expressing ferritin would allow pennate species to store Fe after a transient input, using it to dominate Fe stimulated algal blooms. …
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Scales of variability of phytoplankton composition and biomass in Algoa Bay, South Africa
… has been reported to produce the neurotoxin, domoic acid. Variable environmental conditions with low chlorophyll-a concentrations at Algoa Bay’s marine culture site indicate unsuitable conditions for Pacific oyster production.
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Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis.
… to routinely-monitored marine toxins such as domoic acid (DA). To facilitate regular monitoring, a high-performance liquid chromatography photo diode array (HPLC-PDA) analysis method for the detection of DA was optimised to enable the simultaneous detection of DA and nine cyanotoxins. This …