Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 20 for “"domain dynamics"”.
-
Rab-domain dynamics in endocytic membrane trafficking
… proteins and coordinate them into membrane sub-domains. Such "Rab-domains" constitute modules of molecular membrane identity, which pattern the endocytic membrane system into a mosaic of Rab-domains. The main objective of this thesis research was to link such "static" …
-
Damage Detection and Sensor Placement Strategies for Structures Under Frequency-Domain Dynamics
<p>Identification and monitoring of damage have a growing importance in the maintenance of structures. With advances in high performance computing, numerical modeling tools are becoming more common in anomaly detection and structural damage localization. However, many methods presuppose that …
-
Inverse-Problem Inspired Approaches in the Design of Solids for Frequency-Domain Dynamics
… Due to resonance phenomena in steady-state dynamics, however, objectives used to control dynamic response possess many local minima that may represent poor solutions to a design problem, causing challenges for gradient-based optimization methods. Additionally, designs are typically …
-
Modeling, control, and design of hybrid electrical and thermal energy storage systems
… coolant loops for thermal energy storage. Multi-domain graph-based modeling techniques are used to facilitate modeling, control, and design optimization of the energy storage system. Graph-based models capture multi-domain dynamics in a unified framework. A heuristic control strategy is used, …
-
1/F Noise & slow spin dynamics in chromium, chromium alloys, and disordered iron zirconium
1/f resistance noise studies of the spin dynamics in two magnetic systems are described in this thesis. In chromium, 1 If noise was used as a probe to study spin density wave polarization dynamics. Measurements of the noise anisotropy in a high quality single crystal of Cr revealed a temperature …
-
Percolation and nanosecond fluctuators in V2O3 films within the metal-insulator transition
… is a probe of percolation and the fluctuating dynamics of the two-phase domain structure. We measure voltage noise spectra at both low frequencies (up to 100 kHz) and radio frequencies (between 10 MHz and 1 GHz). At low current densities the voltage noise intensity is quadratic in bias current, …
-
UNIQUE ALLOSTERIC MECHANISM REGULATING PROTEIN-PROTEIN INTERACTION THROUGH PHOSPHORYLATION: A CASE STUDY OF THE CONFORMATIONAL CHANGES IN THE SYK TANDEM SH2 PROTEIN
… Syk is a 72-kDa kinase comprising three folded domains: two SH2 domains and a catalytic domain. The tandem SH2 domains connected by linker A are key to the regulation of Syk activity. Immune signaling through Syk is initiated by the binding of the tandem SH2 to the dpITAMs found on immune cell …
-
Investigating the Effects of Glycochenodeoxycholic Acid on Mutant Murine Norovirus P-Domain Structure and Antibody Interactions
… infection. NoVs contain 90 highly mobile P-domain dimers across their capsid surface with specific P-domain conformations known to facilitate host cell infection and promote immunological evasion. To understand these mechanisms, we investigated a novel murine norovirus (MNV) mutant and the …
-
Investigation of polarization switching over broad time and field domains in various ferroelectrics
… switching over broad time and electric field domains, in various modified Pb-based perovskite ferroelectrics, were systematically performed by ferroelectric switching current transient and bipolar drive P-E responses. Studies were performed from E«Ec to E»Ec, where Ec is the coercive field …
-
Towards understanding molecular, sub-molecular and atomic mechanisms of facilitated target search on DNA
… attenuation of target search. We found that the domain dynamics of Egr-1 plays an important role in DNA scanning, and that by modulating the dynamics, it is possible to alter the kinetic properties of the protein. We also gain some insights into how Egr-1 displaces other proteins from its target …
-
Effects of Secondary Forces on the Primary Interaction and Variable Domain Conformation of Antifluorescein Antibodies
… demonstrated to modulate the antibody variable domains as well as impacting complex stability. Although secondary forces do not dictate antibody specificity (the primary interaction) an understanding of these interactions is critical in evaluating the nuances of antibody/antigen interactions. …
-
Relaxation and Spontaneous Ordering in Systems with Competition
… a complex coarsening system with non-trivial in-domain dynamics respond to perturbations? We choose a cyclic predator-prey model with six species each attacking three others. As a result of this interaction network, two competing domains form, while inside each domain three species play a …
-
Nanostructured ferroelectric materials
… temperature or Curie temperature (TC), domain dynamics, dielectric constant, coercive field, spontaneous polarisation and piezoelectric response. Furthermore, nanoscaling can be used to form high density arrays of monodomain ferroelectric nanostructures, which is desirable for the …
-
Generalization in Planning
… all reinforcement learning problems, the exact domain dynamics are initially unknown, and solutions must be obtained by repeatedly interacting with the environment. We prove the soundness of all our approaches and present empirical results that demonstrate their efficacy across various different …
-
NMR Studies on Protein Dynamics and Its Relevance to Functional Kinetics.
… of a strong relationship between protein's dynamics and its functional kinetics was suggested decades ago. Even though different groups investigated this relationship, technical difficulties and lack of appropriate methodology make full understanding of this relationship quite challenging. …
-
Pattern formations and relaxation dynamics in non-equilibrium systems
… patterns spontaneously form within coarsening domains. Through a systematic investigation of relevant correlation functions, the interface width, and other quantities, we show that the non-trivial in-domain dynamics affect the coarsening process and the interfacial properties. The exponents …
-
Dynamics of lattice vibrations, molecular rotations and spins studied by terahertz spectroscopy
… THz pump-optical probe spectroscopy, THz time-domain electron paramagnetic resonance (EPR) spectroscopy, and twodimensional (2D) THz spectroscopy using either the THz electric or magnetic field. Using the electric fields of two time-delayed strong THz pulses, we have demonstrated 2D THz …
-
Low frequency critical current noise and two level system defects in Josephson junctions
… small tunnel junctions, we have studied the time-domain dynamics of isolated TLSs. We have found a TLS whose dynamics is described by the quantum tunneling between the two localized wells, and a one-phonon absorption/emission switching rate. From the quantum limiting rate and the WKB …
-
High Performance Lead--free Piezoelectric Materials
… understanding of the crystallographic nature, domain structure and domain dynamics of KNN. Since compositions close to x = 0.5 are of primary interest because of their superior piezoelectric activity among other compositions (0 < x < 1), crystallographic and domain structure studies are focused …
-
Transmission Electron Microscopy Study of Domains in Ferroelectrics
This thesis investigates domain dynamics in one of the most well-known ferroelectric materials – polycrystalline BaTiO<sub>3</sub> ceramics, and one of today’s most promising ferroelectric materials for future device applications – mixed-phase BiFeO<sub>3</sub> thin films. The investigations use …