Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"dobutamine"”.
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Dobutamine stress magnetic resonance imaging in tetralogy of fallot
… of stress with pharmacological agents such as dobutamine on ventricular function and whether this can be correlated with the need for pulmonary valve intervention. Therefore, the main aim of this thesis was to determine whether dobutamine stress CMR (DS-MR) has clinical utility in TOF patients …
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Importance of cardiac reserve for evaluation and prediction of cardiac function and morbidity assessed by low-dose dobutamine stress echocardiography
… The cardiac reserve was assessed by low-dose dobutamine stress echocardiography. In both patient studies by dobutamine infusion until an increased baseline heart rate with ~20 bpm, in rats at doses of 10 µg/kg/min and 20 µg/kg/min dobutamine and in mice after an intraperitoneally injection of …
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Širdies magnetinio rezonanso tomografijos vertė, prognozuojant kairiojo skilvelio miokardo kontrakcijos atsistatymą po revaskuliarizacijos /
… and the contractile reserve during low dose dobutamine administration) as predictors of left ventricular segmental and global functional recovery in patients with left ventricular systolic dysfunction undergoing surgical or percutaneous revascularisation. Taking into account previous studies, …
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Cardiovascular function in animal models of metabolic syndrome and type 2 diabetes : the role of inducible nitric oxide synthase (iNOS)
… showed that cardiac contractile response to dobutamine was compromised in the ZDF rats, and this was associated with increased myocardial protein expression as well as activity of iNOS. The formation of peroxynitrite was increased in the heart tissue of the ZDF rats. Selective inhibition of …
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Determination of cardiac output across a range of values in horses by M-mode echocardiography and thermodilution
… pharmacological protocol (dopamine, 4 ug/kg/min, dobutamine, 4 ug/kg/min, and 10 ug/kg detomidine plus 20 ug/kg butorphanol, in sequence). Changes from baseline CO in response to each drug were evaluated, and data was analyzed to determine whether there were any interactions between drug treatment …
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Magnesium sulphate reversal of established bupivacaine electrophysiological cardiotoxicity
… with a positive chronotrophic agent such as dobutamine.
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Evaluation of alterations in cardiovascular structure and function in end-stage renal failure.
… undertook to evaluate the diagnostic accuracy of dobutamine-stress CMR in the detection of haemodynamically‐significant coronary artery disease prior to renal transplantation. Finally, we invasively evaluated coronary endothelial function in the presence of advanced renal dysfunction, and compared …
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Papildomas adenozino vaidmuo mažinant infarkto dydį ir išsaugant kairiojo skilvelio funkciją pacientams, sergantiems ūminiu miokardo infarktu /
… transthoracic Doppler echocardiography, dobutamine stress echocardiography) it was estimated, that adenosine preserves myocardial contractility and coronary flow reserve during the acute phase of myocardial infarction, reduces the final infarct size, improves the recovery of left …
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Einfluss des HMG-CoA-Reduktase-Inhibitors Simvastatin auf Überleben und hämodynamische Parameter im murinen Sepsismodell
… pressure and cardiac output were detected after dobutamine stimulation indicating the well described hyporeactivity to catecholamines that occurs in sepsis. Regarding an acute septic cardiomyopathy a significant cardiac dysfunction was documented accompanied by reduction of left ventricular …
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Magnetic resonance imaging of the right ventricle in human pulmonary hypertension
… interventricular septum. Finally, in Chapter 5, dobutamine stress-CMR was used to determine the individual reasons for right and left ventricular stroke volume impairment during exercise in PH patients. ∆ RV stroke volume appeared limited by diminished contractile reserve as ∆ RVEF was lower in …
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Cardioprotective effects of Glucagon-like Peptide 1 (GLP-1) and their mechanisms
… glibenclamide. A demand ischaemia study uses dobutamine stress echo to compare LV function. The other uses transient coronary balloon occlusion to generate supply ischaemia during GLP-1 infusion, assessed by conductance catheter. A further transient balloon occlusion is also used to assess the …
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Modulation of hippocampal sharp wave-ripple activity in vitro
… In contrast, activation of β1 ARs by dobutamine significantly increased the incidence of SPW-Rs and facilitated induction of both LTP and SPW-Rs within the CA3 network. Suppression of SPW-Rs by NE was linked to presynaptic modulation of transmitter release via α1 ARs-mediated reduction …
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Circulating cell-derived microparticles – potential markers of cardiovascular risk
… conditions. Patients undergoing a dobutamine stress echocardiogram (DSE), for the identification of coronary artery disease, were studied. Patients with a negative DSE exhibited an increase in procoagulant, platelet-derived, endothelial-derived and red blood cell-derived …
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A Relevance Feedback-Based System For Quickly Narrowing Biomedical Literature Search Result
… using a real biomedical data that created using dobutamine (drug name). The data set contains 1,099 original documents. To obtain coherent and reliable evaluation results, two physicians are involved in the system evaluation. Using (30-day mortality) as specific query, the retrieved result …
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In vivo and in vitro aspects of imidazoline-2(1/2)sites within the central nervous system
… agonist methoxamine, but not the β1 agonist dobutamine or the β2 agonist salbutamol, gave rise to significant levels of substitution for the 2-BFI cue. The administration of the α1-adrenoceptor antagonist WB4101, prior to 2- BFI itself significantly reduced levels of 2-BFI appropriate …
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Peri-operative cardiac morbidity: prediction, prevention and the novel role of B-type natriuretic peptide
… cardiac risk prediction at the present time are dobutamine stress echocardiography and dipyridamole thallium scanning. However they are expensive, time consuming and have shown poor positive predictive ability, even in high risk cohorts. Few studies have studied the usefulness of biochemical …
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Diagnostische und prognostische Wertigkeit der kontrastmittelverstärkten Dobutamin-Stressechokardiographie bei herztransplantierten Patienten
Für Patienten im terminalen Stadium der Herzinsuffizienz bleibt häufig als letzte Alternative die orthotope Herztransplantation. Weltweit wurden bis heute 63.000 Herztransplantationen durchgeführt. Postoperativ sind lebenslang engmaschige Kontrolluntersuchungen notwendig, um typische Komplikationen …
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Direkte kardiale Effekte positiv inotroper Pharmaka bei Sepsis-induzierter kardialer Dysfunktion am isoliert perfundierten Rattenherzen
Im Rahmen einer Sepsis kommt es häufig zu einer myokardialen Dysfunktion, der septischen Kardiomyopathie, die den Einsatz positiver Inotropika erfordert. Ziel der Studie ist es, die jeweiligen dosisabhängigen Wirkungen gängiger Inotropika auf die linksventrikuläre Funktion und den …