Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"disulfide cross-linking"”.
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Disulfide Cross -Linking in Protein Microspheres
… of the microsphere shell. Treatment with a disulfide reductant established that disulfide bonds are the covalent cross-link between protein molecules. Mass spectrometry has shown that inter-protein disulfide bonding is not random. The disulfide bonds that do form reflect the electrostatic …
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The Role of Lipid-Free Apolipoprotein A-I and PCPE2 in HDL Metabolism
… structure of lipid-free apoA-I based on chemical cross-linking in conjunction with disulfide cross-linking to define distance constraints. Results indicate lipid-free apoA-I is compact with amino acids 44-186 bundled together with the N-and C-terminal ends folded so that they lie close to one …
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Bioanalytical methods for studies of homocysteine and novel cardiovascular disease indicators
… nanoparticle self-assembly, interparticle disulfide cross-linking, and modification-induced protein conformational changes. This dissertation also continues previous atherosclerotic tissue characterization studies by demonstrating the feasibility of using hybrid organic-immunoaffinity …
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Investigating the molecular biology of aging and extended longevity: Proteomic and genomic analysis of mouse liver
… a strongly oxidizing environment necessary for disulfide bond formation. In these studies, young and aged mouse liver homogenates were separated into enriched sub-cellular fractions, and the ER/mitochondrial fraction was resolved by 2-dimensional gel electrophoresis and then assayed for …
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Genetic and biochemical characterization of YrkF, a novel two-domain sulfurtransferase in Bacillus subtilis
… activity between YrkF and YrkF<sup>C15A</sup>. Cross-linking experiments showed a propensity for the formation of inter- and intramolecular disulfide bonds between the two cysteine residues and indicated that Cys¹⁵ and Cys¹⁴⁹ are located near one another in the 3-dimensional structure of the …