Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"distal histidine"”.
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Control of Ligand Binding to Heme Proteins: The Role of The Distal Histidine
We have investigated the effect of the distal histidine on the recombination rates of CO and O(,2) to sperm whale myoglobin, separated beta chains of normal human hemoglobin and to the beta chains of hemoglobin Zurich. The recombination was measured using flash photolysis from 300 to 40 K, on a …
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Control of ligand binding to heme proteins: The role of the distal histidine
We have investigated the effect of the distal histidine on the recombination rates of CO and O2 to sperm whale myoglobin, separated beta chains of normal human hemoglobin and to the beta chains of hemoglobin Zurich. The recombination was measured using flash photolysis from 300 to 40 K, on a time …
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ANION BINDING TO A HEMEOCTAPEPTIDE AND HEMOPROTEINS - THE MODE AND SITE OF INTERACTION BETWEEN THE DISTAL HISTIDINE AND BOUND LIGANDS IN METHEMOPROTEINS (INFRARED, GLYCERA HEMOGLOBIN).
… - THE MODE AND SITE OF INTERACTION BETWEEN THE DISTAL HISTIDINE AND BOUND LIGANDS IN METHEMOPROTEINS (INFRARED, GLYCERA HEMOGLOBIN).
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FTIR studies of environmental effects on carbonmonoxymyoglobin
… version of Mb with glycine substituted for the distal histidine (His E7).
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Serial and Single Crystal Studies of Ligand Binding to Radiation Sensitive Haem Protein DHP-B
… just its peroxidase function, but its flexible distal histidine that is located at the opening of the distal pocket, this is essential to its peroxidase function. The main aims of this study are to better understand how and also where dehaloperoxidase binds its ligands, demonstrating different …
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Delineation of the active site structure of chloroperoxidase from C. fumago
… the pH values of 2 to 7. The structure of the distal side of the chloroperoxidase heme pocket was also examined. Previous investigations had led to the proposal by a number of investigators that chloroperoxidase possessed a distal histidine, similar to the invariant residue found in the active …
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Magneto-optical spectroscopic studies of multi-heme enzymes
… upon reduction to the diferrous state, whereby a distal tyrosine ligand dissociates from the active site d1-heme, while the ligands at the c-heme switch from bis-histidinyl to histidine/methionine. The processes that take place following re-oxidation of this enzyme have been studied using a …
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Magneto-optical spectroscopic studies of multi-heme enzymes
… upon reduction to the diferrous state, whereby a distal tyrosine ligand dissociates from the active site d1-heme, while the ligands at the c-heme switch from bis-histidinyl to histidine/methionine. The processes that take place following re-oxidation of this enzyme have been studied using a …
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FTIR studies of environmental effects on carbonmonoxymyoglobin
… version of Mb with glycine substituted for the distal histidine (His E7). The IR spectra of CO bound to Mb consists of four bands labelled Ao. A 1· A 2 and A3. The recombination rate of CO toMb following flash photolysis is different for each band. Control may therefore be exercised at the …
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Ligand Diffusion Pathways and Mechanisms for Regulating Oxygen Affinity in Two Model Invertebrate Globins: The E7 Gate and Apolar Tunnel
… involves transient outward movements of the distal histidine (HisE7), which allows ligand migration into the distal portion of the heme pocket. This E7 gate pathway appears dominant in vertebrate Hbs and Mbs. However, a number of invertebrate globins, including the dimeric hemoglobin from the …
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Replacement of Val3 In Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability, Complexes of Sperm Whale Myoglobin G65T With Phenol and Ethylene Glycol, and Structure of A Fragment of Human End-Binding Protein 1 (Eb1)
… dehaloperoxidase (DHP). The distance between the distal histidine and heme iron in G65T Mb increased to 4.56Å (it is 4.30Å in aquomet-Mb), and the turnover number for the oxidative dechlorination of 2,4,6-trichlorophenol (TCP) increased 5-fold. The crystal structure of G65T•phenol complex …