Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"direct stimulation"”.
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Involvement of eicosanoid signalling in epithelial cell migration
… a key process in IBD and CC. This was through direct stimulation, with the eicosanoid leukotriene D4 (LTD4) or indirectly through inducing cyclooxygenase-2 (COX-2; an enzyme involved in the production of various eicosanoids) expression, by activating integrin collagen receptors. We observed …
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Effects of periconceptional undernutrition and twinning on ovine pregnancy
… adrenocorticotropin hormone response to direct stimulation but increased adrenal response to decreased cortisol negative feedback. Twin fetuses grew more slowly in late gestation than singletons. Twins also had a smaller insulin response to arginine and a greater insulin response to …
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An Associative Memory Trace in the Cerebellar Cortex
… that paired peripheral forelimb and periocular stimulation, as well as paired direct stimulation of cerebellar afferent pathways (mossy and climbing fibres) consistently causes a gradual acquisition of an inhibitory response in Purkinje cell simple spike firing. The response also displays …
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Die Bedeutung von Zinkionen für mononucleäre Leukocyten
… cells were examined.For the first time, a direct stimulation of cells by zinc could be shown, which was dependent on zinc concentration and could not be induced by other cations. Even in physiological doses, zinc interacts significantly with intracellular processes. Cell-lines as well as …
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Transcranial Direct Current Stimulation with Individualized Physical Therapy for Chronic Knee Pain
… or exercise. The addition of noninvasive brain stimulation, in the form of transcranial direct stimulation (tDCS), to PT has the potential to reverse maladaptive plasticity, as well as improve pain and functional outcomes beyond those seen with PT in isolation. This study investigated the …
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Identification of a Functional Hotspot on Ubiquitin Required for Stimulation of Methyltransferase Activity on Chromatin
… chromatin structure and function either by directly altering the intrinsic physical properties of the chromatin fiber or by nucleating the recruitment and activity of a host of transacting nuclear factors. Histone ubiquitylation is one class of histone PTMs where the 76 amino acid protein, …
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Modulation der Immunglobulinproduktion bei Ratten mit CD28-spezifischen monoklonalen Antikörpern
… Produktion und Proliferation der Zellen (Direkte Stimulation). In vivo führt Gabe von JJ316 zu einer Erhöhung der Zellzahl in Milz und Lymphknoten mit einem Maximum nach drei Tagen. In vitro führte Behandlung mi mAk JJ316 zu einem Anstieg Th2-spezifischer Immunglobuline. In dieser Arbeit konnte …
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Systems biology approach to understanding the control of glucose metabolism in healthy and apoptotic neurons
… in one or more reaction, making analysis of direct kinetic change in ATP turnover is experimentally infeasible. For these purposes, a comprehensive detailed map of the control distribution in healthy neurons using the metabolic control analysis was obtained for the first time. This …
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Regulation of duodenal mucosal bicarbonate secretion
… intestinal polypeptide and prostaglandin E2 act directly via distinct receptors on the duodenal enterocytes, activating adenylate cyclase and protein kinase A in sequence to initiate bicarbonate secretion. In addition, there is good evidence that the inositol phospholipid and protein kinase C …
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Closed Loop Control of Muscle Contraction using Functional Electrical Stimulation
… with vocal fold paralysis using electrical stimulation is investigated throughout this research work. Functional Electrical Stimulation works by stimulating the atrophied muscle or group of muscles directly by current when the transmission lines between the central nervous system are …
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A Purkinje cell Timing Mechanism. On the Physical Basis of a Temporal Duration Memory.
… patterned input. Training Purkinje cells with direct stimulation of their presynaptic fibers, and pharmacological blocking of interneurons shows that the timing mechanism is intrinsic to the cell itself and not an emergent property of the network. That an individual neuron can learn temporal …
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The Effects of Low Intensity Ultrasound on Chondrogenic Differentiation of Rabbit Mesenchymal Stem Cells In Vivo
… nude mice. While ultrasound group received the direct stimulation with the LIUS in vivo for 20 min every day up to 4 weeks, control group had no LIUS stimulation. In the Study II, PGA-MSCs constructs were divided into four subgroups of the untreated control, LIUS, TGF and LIUS/TGF groups. For a …
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Controlled Migration of Retinal Progenitor Cells Within Electro-Chemotactic Fields
… low – ~5% cells transplanted enter the retina – directly limiting the efficacy of the treatments. Additionally, the cells left behind can have detrimental effects upon the surrounding tissue, resulting in further damage to the retina. Understanding of the mechanisms by which the RPCs migrate into …
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MECHANISMS OF RAPID RESOLUTION OF DIABETES FOLLOWING ILEAL INTERPOSITION SURGERY IN THE RAT
… one to examine the role of lower intestinal stimulation of the ileum without other surgical confounds such as restriction and malabsorption. The general hypothesis is that lower intestinal stimulation may be necessary for improvement in glucose control. In Specific Aim 1, ileal interposition …
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Layer specific differences in the mouse auditory corticocollicular system
… method of parsing out synaptic versus direct stimulation. We contrast this method with the more commonly used time window method. In identified layer 5 and layer 6 corticocollicular recordings, cells show spatial differences in their respective input maps. Layer 5 corticocollicular …