Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"direct mutagenesis"”.
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Transcriptional Regulation of Matrix MetalloProteinase-3 in Rat Brain Astrocytes.
… in induction of MMP-3. EMSA-based study and site-direct mutagenesis revealed that AP-1 is important in induction of MMP-3. Since three AP-1 binding sites (we described them as proximal, middle and distal, respectively according to the distances from start codon) exist in -500 promoter sites, we …
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Propionate induces gluconeogenesis in dairy cattle through direct activation of the bovine cytosolic phosphoenolpyruvate carboxykinase gene promoter
… of bovine hepatocytes allowed examination of the direct effect of propionate on expression of PCK1 mRNA independent of hormonal status. In this study, bovine hepatocytes were isolated from neonatal calves and cultured with propionate, insulin, cAMP, dexamethasone or their combinations. These data …
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Gezielte Modifikation sowie Analyse der Bindungseigenschaften des Histidin Bindeproteins aus Escherichia coli und des GCN4 Leucinzippers aus Saccharomyces cerevisiae
Das Histidin-Bindeprotein (HisJ) gehört zur Familie der löslichen periplasmatischen Rezeptorproteine gramnegativer Bakterien wie Escherichia coli. HisJ ist am Transport von Histidin ins Zytoplasma beteiligt und besitzt für seinen Liganden eine Affinität im nanomolaren Bereich. Durch Austausch eines …