Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"digital detection"”.
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Integrated Microfluidic System for Digital Detection of Extracellular Vesicles
… a microfluidic platform for capture of EVs and digitally detect them with the help of a digital microarray and a smart actuation device for sealing the microwells. The chip achieves the EV quantification by digital Enzyme-Linked Immunosorbent Assay (ELISA) and enzymatic signal amplification. …
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Dynamic Digital Optical Tomography for Cancer Imaging and Therapy Monitoring
… of an instrument for rapid optical imaging using digital detection techniques. In addition to a detailed description of the instrument, three studies are presented: a clinical study detecting breast cancer using dynamic optical imaging; a pre-clinical study monitoring early tumor response to …
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Development of spectroscopic smartphone biosensors for point-of-care applications
… device platform capable of non-amplifying, digital-detection for high-sensitivity diagnostics. In this work, I describe the development of this system, moving from usage-specific benchtop and smartphone based devices demonstrating proof-of-concept capabilities, to a multimodal smartphone …
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Techniques for low jitter clock multiplication
… tuning circuits. This thesis proposes a mostly-digital tuning technique that drastically reduces deterministic jitter in phase realigning clock multipliers. The proposed technique eliminates path mismatch by using a single-path digital detection method that leverages a scrambling time-to-digital …
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Microscale biosensors for HIV detection and viral load determination
… on the complementary measurement, viral load detection, aimed at meeting the ideal criteria described above for a point-of-care diagnostic technology. Our approaches to viral load measurements follow two broad themes. First, we describe an antigen-based approach which leverages immuno-affinity …