Global ETD Search
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Showing 1 to 3 of 3 for “"difluoromethylation"”.
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Late stage 18F-difluoromethylation of N-heteroaromatics
… under flow photoredox conditions. The 18F-difluoromethylation relies on the use of a new 18F-difluoromethylating reagent derived from the Hu’s reagent. This reagent is organic and produces a CHF2 radical under blue LED irradiation, based on previous reported publications. The fluorine-18 …
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Fluorinated Organic Molecules for Medicinal Applications
… sciences make them attractive synthetic targets. Difluoromethylation methods are of exceptional value and a limited number of techniques are available to perform that transformation. The primary method for introducing CF2 groups is through the use of difluoroenolates. Difluoroenolates can be …
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LIGHT AND ELECTRICITY: POWERFUL TOOLS FOR NEW SUSTAINABLE STEREOSELECTIVE SYNTHESIS
… approaches for the monofluoromethylation, difluoromethylation, trifluomethylation and perfluoroalkylation reported in literature have been selected and explained. Taking into account the advantages and the powerful of electrophotocatalysis, it is developed a versatile strategy to generate …