Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 167 for “"differential gene expression"”.
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Macrophage heterogeneity generated by differential gene expression
Restriction data tranferred 2014-07-01T11:19:49-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: ETDs are only available to UIUC Users without author permission
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Differential gene expression analysis of metolachlor treated human liver cells by microarray
1 PDF file (viii, 159 pages)
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Differential Gene Expression in Response to Hypoxia and Acidosis in Chest Wall Deformities and Chondrosarcoma
… of hypoxia and extracellular acidosis on the expression of genes related to the hypoxia response pathway in costal cartilage chondrocytes, two pectus chest wall deformities, and the hyaline cartilage producing cancer, chondrosarcoma. Cells isolated from costal cartilage were incubated under …
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Statistical methods for testing differential gene expression in bulk and single-cell RNA sequencing data
… identify features of the transcriptome (such as genes) that are deferentially expressed (DE) between or among groups of individuals or tissues that are different with respect to some condition (e.g. disease status and treatment). However, because of technical artefacts in RNA-seq technologies and …
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Microarray-based differential gene expression of listeria monocytogenes cultures grown as biofilms and planktonic cells
Listeria monocytogenes is one of the most virulent foodborne pathogens prominent in the food industry. The correlating disease listeriosis infects 2500 individuals in the United States annually of which roughly 625 cases are fatal. Current research is emphasizing that these infections are due to …
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DIFFERENTIAL GENE EXPRESSION DURING ISCHEMIA AND REPERFUSION IN AN EXTRACORPOREAL SMALL BOWEL PERFUSION MODEL IN SWINE
… und einer Induktion der entsprechenden mRNA-Expression kommt. Diese Reaktion zeigte sich schon während der kalten Ischämiezeit, wobei sie nach 20 Stunden KIZ deutlich ausgeprägter war als nach 2 Stunden. Nach Reperfusion kam es zu einer mukosalen Schädigung, wobei eine verlängerte kalte …
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Differential gene expression in Behcet's disease and differential anti-tumor effects of Tim3 pathway blocking molecules
PART I Differential expression of genes according to colchicine responsiveness in Behçet’s disease Behçet disease (BD) is a chronic relapsing, systemic inflammatory disorder which is treated with colchicine. However, some patients are not responsive to it. In this study, I wanted to explore the …
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Differential gene expression and molecular mechanisms associated with development of pale, soft and exudative (PSE) turkey meat
… of molecular-based approaches such as genetic markers for animal selection or pathway intervention to prevent development of this meat defect have been suggested as a potential long-term solution. However, molecular mechanisms associated with this alteration remain unclear. The overall …
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Characterization of the Role of Differential Gene Expression and RNA Editing in Drosophila Tonic and Phasic Motoneuron Diversity
How differential regulation of gene expression programs across neuronal subtypes leads to their unique morphology, membrane excitability and synaptic properties is poorly understood. Protein expression and function within neurons depends on numerous transcriptional and post-transcriptional …
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Differential gene expression analysis reveals functional roles of cryptic orange-pigmented organ in the colorless head kidney of Antarctic icefishes
… in Antarctic fishes or teleost fishes in general. To assess the tissue type and functions of this cryptic orange body, we performed RNA sequencing and analyzed the orange body transcriptome relative to the surrounding head kidney tissue. We found 5,263 differentially expressed genes in the …
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A Time-Course Analysis of Behavioral Plasticity and Differential Gene Expression Patterns in Response to Density in Schistocerca americana (Orthoptera: Acrididae)
… behavior did not significantly change over time. Gene expression of the following three genes suspected of having a role in behavior change were investigated based on studies of S. gregaria: protein kinase A (PKA), L-Tryptophan-5-monooxygenase (T-5), and Aromatic L-amino acid decarboxylase …
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Differential gene expression and immune regulatory mechanisms in parasite-resistant hair and susceptible wool sheep infected with the parasitic nematode, Haemonchus contortus
… greater in hair sheep compared to wool sheep. Gene expression was measured between hair and wool lambs for abomasal and lymph node tissues using bovine cDNA microarrays and real-time RT-PCR. Microarray analysis revealed cell survival, endosome function, gut motility, and anti-coagulation …
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Crosstalk between steroid and GnRH receptors in regulating gene expression in the mouse LÇT2 gonadotrope cell line
… regulating target receptor mRNA and protein expression in a pituitary gonadoptrope cell line, and discuss how crosstalk signalling may contribute to differential gene expression.
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The role of DNA methylation in transcriptional regulation of the human type 1 alpha 2 collagen (COL1A2) gene
… one alpha 2 (COL1A2) chains. Reduced collagen gene expression is almost always correlated with pathological conditions and cellular transformation. Numerous studies have suggested that methylation of the cytosines in CpG dinucleotides is inversely correlated with transcriptional activity and …
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The Effects of Temporal Cold Exposure and Caste Differences on Gene Expression and Epigenetics of Common Bumble Bee Species
… I first investigated cold-induced temporal gene expression changes in a common eastern species, Bombus impatiens. Findings suggest that differential gene expression of thoracic muscles peaked 10 minutes after chill coma recovery and was primarily characterized by metabolic shifts favoring …
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The role of genetic alterations in the gut-joint axis of Crohn's disease and Spondyloarthropathies
… CD and SpA, we demonstrate in this work a genetic connection between these two disorders. Carriership of CD-related CARD15 polymorphisms in SpA patients is associated with the presence of chonic gut inflammation, similar to CD. Whether these genetic variants in CD and SpA play a direct role …
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Investigation of the genetic basis of antibiotic resistance in Mycobacterium tuberculosis
… marker suggests that other factors, such as differential gene expression, may play a role in the development of drug resistance in M. tuberculosis. This investigation aims to both develop and evaluate rapid genotypic assays for the detection of resistance to both first- and second-line drugs …
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Profiling of gene expression in bread wheat (Triticum aestivum L.) line PI 137739 in response to Russian wheat aphid (Diuraphis noxia Mordvilco) feeding
… PI 137739 is known to contain the RWA resistance gene, Dn1. The study was conducted by utilising and combining a vast array of molecular biological techniques. Chapter 1 introduces the reader to a summary of the resistance responses observed within infested plants. A detailed description of the …
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Characterization of cyclic di-GMP binding by the sole Borrelia burgdorferi and Borrelia hermsii PilZ domain-containing proteins
… involving tick vectors and mammalian hosts. Differential gene expression is central in their survival in various environmental conditions. C-di-GMP has been demonstrated to be important in bacterial adaptation. Borrelia deletion mutant phenotypes have shown that c-di-GMP regulates motility, …
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