Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 36 for “"diarrheal disease"”.
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The Impact of Climate Variability and Conflict on Childhood Diarrhea and Malnutrition in West Africa
… climate variability and armed conflict impacts diarrheal disease and malnutrition among young children in West Africa. Two studies examine the associations between climate and diarrheal disease across the whole study area – ten countries in West Africa during the period 2008-2013. The third …
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Immunomodulation by subclinical persistent infection with Helicobacter hepaticus
… with particular usefulness for modeling human diarrheal disease or inflammatory bowel disease. Infection with Helicobacter hepaticus is subclinical and persistent in C57BL/6 mice, but causes disease in susceptible strains and immunodeficient mice. To test the hypothesis that subclinical …
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WATER QUALITY AND WATERBORNE DISEASE ALONG THE NIGER RIVER, MALI: A STUDY OF LOCAL KNOWLEDGE AND RESPONSE
… of and response to water quality and waterborne diseases in relation to seasonal changes in the Niger River Inland Delta. The study draws on field data collected in four villages along the Niger River in the Mopti district of Mali during September 2008. The major findings suggest: (1) water use …
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WATER QUALITY AND WATERBORNE DISEASE ALONG THE NIGER RIVER, MALI: A STUDY OF LOCAL KNOWLEDGE AND RESPONSE
… of and response to water quality and waterborne diseases in relation to seasonal changes in the Niger River Inland Delta. The study draws on field data collected in four villages along the Niger River in the Mopti district of Mali during September 2008. The major findings suggest: (1) water use …
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The Impact of Borehole Wells and a Hygiene and Sanitation Program on Diarrhea: Evidence from Rural Southwest Uganda
<p>Diarrheal disease is the second leading cause of death for children under age five, killing approximately 2,089 children a day (WHO, 2013). Clean water access, sanitation facilities, and good hygiene behavior are solutions to decreasing child mortality and morbidity caused by fecal …
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The coaggregative abilities of lactobacilli and Campylobacter jejuni
… is one of the main bacterial causes of foodborne diarrheal disease in humans. The aim of this study was to analyze the coaggregative abilities of lactic acid bacteria and C. jejuni as a means to reduce the colonization of C. jejuni in poultry. In this study, various lactic acid bacteria were …
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The Challenges and Opportunities in Monitoring and Modeling Waterborne Pathogens in Water- and Resource-Restricted Africa: Highlighting the critical need for multidisciplinary research and tool advancement
… limiting the success of current waterborne disease management strategies and several existing research hurdles that continue to impede characterization of microbial transmission and transport. In this work, the Chobe River watershed in Northern Botswana serves as a target study site for the …
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As Evaluation of Methods Employed in the Detection of Pathogenic Escherichia Coli
… the past years in sanitation and infant care, diarrheal disease, including epidemic diarrhea of the newborn, still contributes to a large extent to the morbidity in this age group. Investigations have proven that infantile diarrhea is not a monoetiological disease. In some outbreaks members of …
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Can Community Water Projects Combat Child Diarrhea? Results From the Solomon Islands
… water projects have the ability to mitigate diarrheal disease. A strong and persistent belief thinks that community water projects do have the means, however, over the decades empirical work commonly finds this to simply not be true. This study expands the research question to the Solomon …
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Molecular modeling of bacterial polysaccharide antigens to inform future vaccine development
… prevalence and severity of bacterial infectious diseases worldwide, preventing countless deaths. The effectiveness of a vaccine can be extended if the selected vaccine strains in a multivalent vaccine cross-protect against non-vaccine strains. Detailed knowledge of antigen structure and …
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Characterization of Campylobacter, Salmonella, and Diarrheagenic Escherichia Coli from Food, Food Waste and Water in the Chobe Region of Botswana
Introduction and Justification: Diarrheal disease is a leading cause of death in children in low- and moderate-income countries. Food, food waste, and water are all vehicles that can promote the spread of diarrheal disease-causing bacteria like Campylobacter, Salmonella enterica, and E. coli. …
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Molecular Detection for the Apicomplexan Parasites Cyclospora cayetanensis and Cryptosporidium spp.
… Apicomplexan parasites that can cause severe diarrheal disease in children and immunocompromised hosts. Diagnostic challenges using routine diagnostic methods lead to an underreporting of these parasites, particularly in resource-limited settings. Establishing affordable molecular detection …
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Characterization of human astrovirus in pediatric patients with diarrhea from rural communities of Limpopo South Africa
… has been identified as a causative agent of diarrheal disease worldwide especially in young children under five years of age. Recent reports in South Africa demonstrated HAstVs as a potential pathogen associated with diarrhea. The aim of this study was therefore to investigate the genetic …
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Giardia trophozoite-secreted proteins and their effects on intestinal epithelia
Giardia is a major cause of diarrheal disease worldwide. It is a flagellated cyst-forming enteric pathogen that inhabits the lumen of the small intestine. Two genetically distinct lineages (assemblages A and B) are of public health relevance and are often associated with water-borne outbreaks. Yet, …
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Effects of different water sources on MS2 and porcine rotavirus reduction in biosand filters
Diarrheal diseases caused by pathogens remain a significant cause of death in developing areas, especially for children under the age of five. Biosand filters (BSFs) are a promising technology implemented worldwide that can effectively reduce levels of bacteria and bacteriophages. However, the …
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Modeling the Impact of Flood Pulses on Disease Outbreaks in Large Water Basins with Scarce Data
… These flood pulse events have been linked to diarrheal disease outbreaks in the local population, the magnitude of which is associated positively with flood height. Modeling these interactions can advance our ability to predict events and develop mitigation and prevention actions. However, …
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Butyrate Sensing by Campylobacter jejuni Impacts Bacterial-Host Interactions
… avian species and a leading cause of bacterial diarrheal disease in humans, recognizes intestinal niches that support growth by sensing molecular cues produced by the microbiota. How C. jejuni senses and responds to microbiota-generated SCFAs and organic acids is not understood. Herein, I …
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Characterization of the Activation of the FlgSR Two-Component System in Campylobacter Jejuni
… relationship, human infection can cause diarrheal disease. In both scenarios flagellar motility is crucial for promoting optimal host interactions, as non-motile C. jejuni colonize the gastrointestinal tracts of commensal hosts at levels significantly lower than motile isolates and are …
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The Novel Long Non-Coding RNA Nostrill Regulates Intestinal Epithelial Defense Against Cryptosporidium parvum and Modulates Microglial-Mediated Neurotoxicity
… protozoan parasite that causes significant diarrheal disease and an important opportunistic pathogen in the immunocompromised. Induction of Nostrill was triggered by NF-κB signaling and was observed to enhance epithelial defense by decreasing parasitic infection burden. Nostrill participates …
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Monitoring and evaluation of a ceramic water filter and hand-washing intervention in Northern Ghana
… water management, hand-washing practices, diarrheal disease prevalence, and respiratory disease prevalence. In total 429 households were sampled from 20 villages, and the results from 10 villages are reported in this thesis. Overall, 98.6% of the survey population uses surface water as a …
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