Global ETD Search
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Showing 1 to 17 of 17 for “"di(2-ethylhexyl) phthalate"”.
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Prenatal exposure to di-(2-ethylhexyl) phthalate (DEHP) affects reproductive outcomes in mice
Made available in DSpace on 2015-01-21T19:48:35Z (GMT). No. of bitstreams: 2 Sarah_Steinmann.pdf: 3164394 bytes, checksum: 328ad683ab1c9c5ace3db3f526440b41 (MD5) MS Thesis.docx: 4955493 bytes, checksum: c6340d08f5b331a08772527c673f9a8c (MD5)
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The transgenerational effects of Di(2-ethylhexyl) phthalate on female reproduction in mice
Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer used to confer flexibility and stability in common polyvinyl chloride products. DEHP can be found in numerous consumer products and is a ubiquitous chemical. Humans are exposed to DEHP daily due to its widespread use and ability to leach from out …
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Mechanisms by which di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate disrupt ovarian folliculogenesis and steroidogenesis
Di(2-ethylhexyl) phthalate (DEHP) is a synthetic plasticizer used in the manufacturing of common polyvinyl chloride consumer, medical, and building products. Humans are exposed to DEHP on a daily basis because of its high production volumes, incorporation into widely used products, and its ability …
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The effects of di (2-ethylhexyl) phthalate (dehp) on lesion development in a mouse model of endometriosis
Endometriosis is a common gynecological disorder affecting 6%–10% of women of reproductive age and 35%–50% of women experiencing chronic pelvic pain and/or infertility. The most widely accepted mechanism of this disease is the entry of endometrial cell aggregates into the peritoneal cavity via the …
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Changes in Hippocampal Plasticity and HPA Axis Function Following Postnatal Exposure to Di(2-Ethylhexyl) Phthalate in Rats
Phthalates are known to affect the development of regions within the hippocampus, however the mechanisms of these toxic effects are not well known. Stress is also known to have detrimental effects on the hippocampus. This study aimed to determine whether phthalates affect hippocampal development, …
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Prenatal exposure to di-(2-ethylhexyl) phthalate and high-fat diet synergistically disrupts mouse fetal oogenesis and affects folliculogenesis
Di-(2-ethylhexyl) phthalate (DEHP) is a chemical that is widely used as a plasticizer. Plasticizers are chemicals that are added to materials to increase flexibility, durability, and strength. DEHP is abundant in products such as food storage containers, containers of personal care products, …
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Glial activation in a mouse model of endometriosis and impact of Di(2-ethylhexyl) phthalate on glial cells, ileum, and colon
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
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The immediate and long-term consequences of temporary exposure during adulthood to di(2-ethylhexyl) phthalate and diisononyl phthalate on female reproduction
… number of oocytes in the form of the primordial follicle pool. Primordial follicles are composed of an oocyte surrounded by supporting somatic cells. Activated primordial follicles will grow through the primary, preantral, and antral follicle stages before ovulating. Proper maintenance of …
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Do Elevated Levels of Glutathione Decrease the Toxicity of Plasticizers in Mouse Liver Cells?
Phthalates are esters of phthalic acid that play a crucial role in the manufacturing industries for enhancing the properties of plastic materials. Di-(2-ethylhexyl) phthalate (DEHP) is one of the most common phthalates used in a variety of products including food packaging and medical equipment. …
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The effects of environmentally relevant toxicants on female reproduction and embryo development
… body weight, stress, alcohol, drug abuse, diets, and genetics. A novel culprit that is now associated with reproductive failure is exposure to endocrine disrupting chemicals (EDCs). These chemical compounds can interact with the endocrine systems in humans and animals by influencing hormone …
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Distillation of a Binary Mixture in the Centrifugal Molecular Still
… phenomena of a binary mixture over a rotating disk and under conditions of molecular distillation. These phenomena were studied using a modified version of the commercially designed centrifugal molecular still, CMS-5.<br/><br/>A mathematical model was developed which relates the equations of …
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Model-based Exploration of Chemical Absorption and Metabolism Kinetics in the Human Gastrointestinal Tract
… chemical screening and prioritization. This dissertation advances the understanding and predictions of chemicals' Fbio from the perspectives of chemical properties and mass-balance modeling. First, the rate at which a chemical can transport across membranes is an important indicator of how …
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Mechanisms underlying establishment and maintenance of pregnancy
… stromal cells are exposed to hypoxic conditions in vitro, we observed a striking enhancement in HIF2α expression. Further studies revealed that HIF2α regulates the expression of several metabolic and protein trafficking factors, including RAB27B, at the onset of implantation. RAB27B is a …
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Exposure to Phthalate Mixtures and Inner-City Pediatric Allergic Disease and Airway Inflammation
Phthalate plasticizers are found in consumer products and home furnishing materials. Phthalate urinary metabolites are detected in nearly every sample in population-based studies indicating widespread exposure. Prior epidemiologic studies have associated vinyl flooring, a proxy for phthalate …
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Impacts of prenatal phthalate and bisphenol exposure on infant cognition and early language development
… impacts of prenatal exposure to endocrine disrupting chemicals including bisphenols and phthalates are a growing public health concern. Bisphenols and phthalates are used in plastic consumer products, food and drink packaging and containers, personal care and household products, medical …
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Characterizing the impact of phthalates on the female gastrointestinal tract and reproductive system during adulthood
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms
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Emissions of Phthalate Plasticizer from Polymeric Building Materials
… greater than that experienced outdoors. Phthalate esters have been recognized as major indoor pollutants. They are mainly used as plasticizers to enhance the flexibility of polyvinylchloride (PVC) products, as well as in humectants, emollients, and antifoaming agents. Phthalates are found …