Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 34 for “"developmental regulation"”.
-
Developmental Regulation of the Murine CD4 Gene
<p>CD4 is a membrane bound glycoprotein that plays an important role in T cell development and activation. An extensive analysis of the CD4 locus identified potential transcriptional control elements located 5' of the promoter and within the first intron. Since the molecular mechanism for the …
-
Developmental Regulation of Oil Deposition in Arabidopsis Seeds
… development. In an attempt to understand the developmental control of storage product accumulation, we observed the expression time course of the five transcripts. The sequential expression of these factors during seed fill suggests differentiation of their normal responsibilities. By …
-
Developmental regulation of DNA replication in Drosophila melanogaster
… undertook a screen to identify factors affecting developmentally regulated, variant cell cycles during D. melanogaster embryogenesis. We identified a class of mutants with apparently polyploid cells in normally diploid tissues indicating a failure to maintain mitotic cycles.
-
Developmental regulation of DNA replication initiation in Drosophila
Developmental gene amplification in the ovarian follicle cells of Drosophila provides a powerful system for the study of metazoan DNA replication. Amplification produces 100kb gradients of amplified DNA through repeated rounds of origin firing and bidirectional movement of replication forks from …
-
Developmental regulation of smooth muscle contraction in the urinary bladder
… We have used mice to study the contractile regulation of urinary bladder smooth muscle during the fetal period. We found that nerve-induced contractions are mainly dependent on muscarinic receptor activation in the newborn whereas adult bladders are equally dependent on muscarinic and …
-
Developmental regulation of the alpha(7) integrin chain during myogenesis
… on skeletal muscle cells. Its expression is developmental regulated during myogenesis. Not only is the expression of $\alpha$7 transcripts increased upon myogenic differentiation, differential splicing of transcripts is also observed at that time. This differential splicing of $\alpha$7 …
-
Developmental Regulation of Mitochondrial Function in Ovine Fetal Skeletal Muscle
… of the adult offspring. However, the normal developmental profile of skeletal muscle mitochondrial function as the fetus prepares for the increased metabolic challenges associated with extrauterine life, is not well characterised. The hormones, cortisol and triiodothyronine (T3) are known to …
-
Environmental and developmental regulation of carbon cycling in a warm-temperate forest
Anthropogenic emissions of CO2 and other greenhouse gases have lead to a current atmospheric CO2 concentration that is unprecedented in the recent geological history of the earth. Nearly half of anthropogenic CO2 emissions have been sequestered in the terrestrial biosphere and oceans, slowing the …
-
Developmental Regulation of Prion Expression in Cattle and Mouse Embryonic Stem Cells
… retinoic acid (RA) resulted in an earlier up-regulation of PrPC and nestin (day 12 vs. day 16; P < 0.05). In addition, immunofluorescence studies indicated co-expression of PrPC and nestin in the same cells. The results of these experiments suggested a temporal link between PrPC expression and …
-
Whole-organism integrative expressome for C. elegans enables in silico study of developmental regulation
… map of gene expression across the entire developmental timeline of the organism, with the goal to find genomic features that regulate cell division and tissue differentiation. Contingency testing was performed to find correlations between thousands of gene attributes (e.g. the presence or …
-
Dietary and Developmental Regulation of Nutrient Transporter Gene Expression in the Small Intestine of Two Lines of Broilers
… were conducted to evaluate the dietary and developmental regulation of nutrient transporter mRNA abundance in the small intestine of two lines of broilers selected on corn-based (Line A) or wheat-based (Line B) diets. Abundance of mRNA was quantified in all experiments using real time PCR …
-
Developmental Regulation of the Expression of Nutrient Transporter and BrushBorder Membrane Hydrolase Genes in the Small Intestine of Piglets
The objective of this study was to evaluate developmental regulation of the expression of nutrient transporter and brushborder hydrolase genes in the small intestine of piglets. Seventy piglets from seven sows were killed at birth (d 0), during suckling (d 1, 3, 7, 14, 21) and postweaning (d 22, …
-
Molecular Cloning and Functional Characterization of a Turkey Intestinal Peptide Transporter (tPepT1), and Developmental Regulation of PepT1 Expression in Turkey and Broiler Embryos
… a possible substrate inhibition. To study developmental regulation of PepT1 in broiler and turkey embryos, 12 Nicholas turkey or Cobb x Cobb broiler embryos (six males and six females) were sampled daily from 5 d before hatch to the day of hatch (d 0). The abundance of PepT1 mRNA in the …
-
Glycine receptors in the developing rat spinal cord
Inhibitory glycine receptors (GlyRs) undergo developmental regulation with α2 subunits most abundant at prenatal and early postnatal stages, and α1 subunits predominating in adults. In comparing the relative amounts of mRNA for two known splice variants of the α2 subunit, α2A and α2b, in the rat …
-
An Analysis of Gene Regulatory Evolution Within the Centrarchids
… different studies analyzed the divergence of developmental regulation among centrarchid fishes (Centrarchidae, Perciformes). The degree of divergence between the regulatory genes of different species was assessed investigating the extent to which morphological and molecular development is …
-
Developmental and estrogen regulation of Xenopus laevis retinol-binding protein gene expression
The developmental regulation of the estrogen-regulated serum retinol-binding protein and estrogen receptor genes in Xenopus embryonic livers has been examined. Serum retinol binding protein (RBP) mRNA is detected exclusively in liver tissue in both adult Xenopus laevis and in tadpoles. RBP mRNA is …
-
MicroRNAs in early embryonic development : dissecting the role of miR-290 through miR-295 in the mouse
MicroRNAs mediate developmental regulation of gene expression via translational repression of target mRNAs. Targeted deletion of the miRNA biogenesis machinery in the mouse has demonstrated essential roles for miRNAs during early development. In this thesis, I have examined the role of a family of …
-
Hiding in plain sight: unveiling cryptic diversity and patterns in bumble bees
… mimicry. Yet nothing is known about the developmental regulation of these color patterns. As a first step in exploring the developmental regulation of color, I mapped the color patterns across the body of individual species with high resolution using a grid map. My collaborators and I use …
-
Induction, Selection, and Characterization of Ethylene -Insensitive Mutants in Antirrhinum Majus (Snapdragon)
… of mutant lines included investigation of developmental regulation of vegetative and floral tissues in using five ACS and two ETR genes. Gene expression patterns were also investigated when floral spikes were exposed to 250 muM ACC either with or without pre-treatment with 1-MCP. Additional …
Page 1 of 2