Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 304 for “"detoxification"”.
-
In-Detoxification: Therapeutic architecture toward healing substance abuse
This study explores rehabilitation by means of therapeutic architecture, to rehabilitate individuals from substance abuse and addiction. The study aims to understand how rehabilitation can benefit the community, facilitated by a community orientated program for individuals. The site used for the …
-
Biological Evaluation and Detoxification of Cassava (Manihot Esculenta Crantz)
Made available in DSpace on 2014-12-13T19:42:44Z (GMT). No. of bitstreams: 1 7804161.pdf: 4128816 bytes, checksum: 12fee3453ab4b6b9bc91259badddc569 (MD5) Previous issue date: 1977
-
Toxicity and detoxification of imidacloprid in mouse ovarian follicles
Neonicotinoids are synthetic nicotine derivates synthesized with high affinity for invertebrate nicotinic acetylcholine receptors (nAChRs) and comparatively low affinity for mammalian nAChRs. They are used in diverse industries ranging from commercial agriculture to veterinary pharmaceuticals, …
-
The Role of Glutathione Transferases in the Detoxification of TNT
… remediation system. Key genes involved in the detoxification of TNT by plants have been recently identified by expression studies and the encoded enzymes characterised. This has lead to the thorough investigation of the enzymes in the pathway of TNT detoxification; Phase I transformation …
-
Insecticide detoxification in the navel orangeworm Amyelois transitella (Lepidoptera: Pyralidae)
… which suggests that P450s are involved in detoxification of pyrethroid insecticides. Only azinphos-methyl was a substrate for GSTs in A. transitella, as evidenced by diethyl maleate synergism assays. Neither PBO nor DEM influenced the toxicity of the anthranilic diamide chlorantraniliprole. …
-
Xenobiotic detoxification in the navel orangeworm Amyelois transitella (Lepidoptera: Pyralidae)
… was carried out using BLAST homology. As detoxification of phytochemicals, mycotoxins, and pesticides is mediated at least in part by P540 enzymes, developing genomic resources for characterizing P450s and elucidating their function in this insect will aid in management efforts for this …
-
Enzyme-based detoxification of organophosphorus neurotoxic pesticides and chemical warfare agents
… the catalytic efficiencies of these two major detoxification enzymes were characterized with substrates representing each class of OP neurotoxin, phosphotriester, phosphothioate and phosphofluoridate. OPH presents superior kinetic parameters with each OP class tested. Variants of OPH were …
-
Resin Detoxification in Dendroctonus ponderosae: Functional Characterizations of Cytochrome P450 Proteins
A growing epidemic of pine tree deforestation in North America can largely be attributed to a particular pest, the Mountain Pine Beetle (MPB, Dendroctonus ponderosae). Coupling pheromone-coordinated mass attacks with an ability to resist the trees' natural defenses allows the beetles to overwhelm …
-
Structural Dynamics and Reaction Reversibility of Specific vs. Promiscuous Detoxification Enzymes
Detoxification enzymes occupy a unique niche in biology. Unlike most enzymes with defined roles in biochemical pathways, detoxification enzymes have evolved to bind and metabolize many chemically unrelated structures ¬– to be promiscuous – rather than to optimize catalysis towards a preferred …
-
Mechanisms of anaerobic nitric oxide detoxification by Salmonella enterica serovar Typhimurium
… of RNS that damages bacterial DNA and proteins. Detoxification of NO is essential during infection to allow Salmonella to survive and replicate within macrophages. Three enzymes are currently known to help Salmonella to detoxify NO, but their deletion, however, does not eliminate Salmonella’s …
-
Chemical mixtures and interactions with detoxification mechanisms and biomarker responses in fish
… in animals. This thesis investigates how detoxification mechanisms are affected by exposure to chemicals alone or in mixtures. Cytochrome P450 (CYP) enzymes and efflux pumps have key roles in the detoxification and elimination pathways of many structurally different chemicals and are …
-
Differential detoxification strategies in closely related herbivore species across a sharp ecotone
… in N. lepida and N. bryanti? 2) How does CYP detoxification ability limit diet switching in N. lepida and N. bryanti? To answer these questions, we developed an in vitro assay to isolate liver CYPs and test their activity on plant extracts as well as individual compounds, using LCMS-TOF to …
-
Antioxidant Genes in <i>Apis mellifera</i>, Their Implication in Pesticide Detoxification
<p>The effect of pesticides on <em>Apis mellifera </em>mortality as well as their effect on the transcriptional regulation of antioxidant genes was the aim of this study. Unlike previous studies, the work here shows the combined effects of pesticides imidacloprid and coumaphos on worker bees at …
-
Effects of Nutrients and Minerals on Growth and Detoxification in Phytophagous Insects
… insect performance is by affecting activities of detoxification enzymes, thereby altering susceptibility to host plant allelochemicals. In this study I examined the influence of antioxidant vitamins, minerals, and compounds that affect mineral bioavailability on performance and detoxification in …
-
Regulation of Hepatic Detoxification Enzymes by Glucosinolate Breakdown Products in Cruciferous Vegetables
In conclusion, there is a molecular interaction between crambene and I3C that explains the synergism in phase II enzyme induction after exposure to combinations of these two components. In addition to this, active glucosinolate breakdown products studied here also have anti-promotional effects …
-
Immunoprotective effects of lipopolysaccharide detoxification by a novel microbial-derived alkaline phosphatase
Lipopolysaccharide (LPS) is a major outer cell wall component of Gram-negative bacteria, including Escherichia coli and Salmonella enterica, which have important health and economic consequences in animal agriculture. LPS is a recognized endotoxin that stimulates toll-like receptors, which are …
-
Effect of Temperature on Absorption and Detoxification of Ddt in Musca Domestica L
Made available in DSpace on 2015-05-12T17:15:35Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 0005219.PDF: 7612009 bytes, checksum: 2e7f55cc0568c2db451a5c02a649d6a6 (MD5) Previous issue date: 1953
-
Predictors of detoxification services use in Alberta: a provincial socio-demographic and utilization analysis
Detoxification is the first step in the substance use and addictive behaviours recovery process, serving as the transition between dependency and reduced use or abstinence. Completing detoxification is an important milestone in initiating recovery and remission of withdrawal symptoms, as well as …
Page 1 of 16