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Showing 1 to 1 of 1 for “"designed multiple ligands"”.
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The synthesis of 5-HT2 receptor designed multiple ligands to investigate the role of the 5-HT2AR and the 5-HT2CR in cocaine addiction
… target these GPCR dimers and oligomers bivalent ligands have been synthesized. Previously synthesized bivalent ligands have demonstrated increased affinity and potency when compared to administration of the monomers. The aim of this project is to synthesis homodimeric 5-HT2A R antagonists, …