Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 289 for “"dermal"”.
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Hydrogels for dermal applications
… to skin and can be used for topical or trans dermal release of active compounds for therapeutic or cosmetic use. The suitability of a range of monomers and initiator systems for the production of skin adhesive hydro gels by photopolymerisation was explored and an approximate order of monomer …
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Mechanism of Metformin Action in Dermal Fibroblasts
… activity in hepatocytes. However its effects in dermal fibroblasts are unknown. Furthermore, up to 90 percent of burn patients develop hypertrophic scars due to dysregulated collagen secretion, which can lead to functional impairment due to excessive collagen deposition associated with …
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Gene expression in post mortem dermal tissue
… thesis, the biological material selected was dermal tissue from pigs, since the skin offers a number of advantages for study in a forensic context, such as ease of harvesting and a slower rate of degradation than most other soft body tissues. Initial chapters describe the development of …
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Functional Heterogeneity of Fibroblasts In Dermal Wound Healing
… therapeutic approaches are critically important. Dermal fibroblasts are critical players in cutaneous wound healing, possibly lending their contractile properties and extracellular matrix (ECM) remodeling functions to promote effective tissue repair. Dermal fibroblasts are also postulated to …
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Dermal exposure to polycyclic aromatic hydrocarbons among workers
Contains fulltext : mmubn000001_180842978.pdf (Publisher’s version ) (Open Access)
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Colloidal microgels as (trans)dermal drug delivery systems
… controlled drug delivery system) for either dermal or transdermal delivery. The experiments conducted in this project were, firstly, to investigate the uptake and release of model compounds with different physico-chemical properties (i.e. solubility and logKoct/w) to and from two colloidal …
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Walleye dermal sarcoma virus Orf C: a potential oncolytic therapy
… of the included species is presented. Walleye dermal sarcoma virus (WDSV) is a complex retrovirus that causes the growth of multifocal, cutaneous tumors in walleye fish (Sander vitreus vitreus). These virus-induced tumors spontaneously regress on a seasonal basis. The WDSV genome encodes three …
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Investigation and control of dermal fibroblast signaling during injury repair
… regulates the injury contraction process in a dermal microtissue on a chip model. We found that a balance of tissue forces generated via RhoA activation is critical for injury contraction, and that spatially localized RhoA activation can recruit new cells to participate in injury contraction. …
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Design of flexible puncture resistant gloves inspired by natural dermal armors
For the purpose of providing protection against potential environmental and physical threats, many animal species have developed hierarchical and heterogeneous biological materials. In turn, scientists and engineers have been inspired by the design of these biological materials and are working to …
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Computational Modeling and Simulation Study of Dermal Wound Healing Proliferative Phase
Dermal wound healing proliferative phase is a complicated physiological process in which many growth factors, cell types and matrix components participate. The process must be well coordinated to restore the structural and functional integrity of tissue injured. Many disorders interrupting healing …
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Comparison of Epidermal and Dermal Fingerprints Collected from Thiel-embalmed Bodies
Direct comparison of dermal and epidermal fingerprints can be vital to the identification of bodies where the epidermal skin layer is no longer available for fingerprinting. It has been reported that identification based on the comparison between dermal and epidermal fingerprints is possible, …
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The Role of Dermal Architecture in Wound Healing and Tumour Differentiation
… done in the laboratory has identified that the dermal matrix composition drives tumour development in patients with RDEB (Ng, Pourreyron et al. 2012), showing that normal cells can inhibit the proliferation and expansion of tumour cells and that the proteins type 5 collagen alpha 1 (COL5A1) and …
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Production of Dermal Inspired Collagen Architectures by Lyophilisation and Electrophoretic Deposition
Collagen scaffolds have been used successfully as dermal regeneration templates in clinical applications, but most do not recapitulate the natural tissue structure and are often combined with synthetic membranes to afford additional barrier properties. This work aimed to produce dermal-inspired …
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Comparison of Epidermal and Dermal Fingerprints in Elderly Individuals: a Pilot Study
In cases of forensic fingerprint identification dermal prints are encountered and used less frequently. Although previous research established the relationship between epidermal and dermal fingerprints, there is a lack of literature detailing identifications based on the comparison of these two …
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Building a Better Scar: Re-engineering Extracellular Matrix Structure in Dermal Scars
… of the rate of healing. In vitro: Primary murine dermal fibroblasts were isolated from the whole dermis of 3-4 week old transgenic mice expressing collagen 1(α2) GFP-tpz. Cells were sorted for expression via FACS and plated on prealigned collagen substrate for 7 days under conditions favorable to …
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Dual-Chambered Membrane Bioreactor for the Dynamic Co-Culture of Dermal Stratified Tissues
… skin scaffolds for clinical use and in vitro dermal models. Throughout this work we studied 3D printing and bioreactor strategies for the simultaneous physiologic and topographic reconstruction of burnt facial skin tissues. First, we formulated a keratin-based bioink that can be used for 3D …
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