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Showing 1 to 5 of 5 for “"denosumab"”.

  1. Challenges in the Pharmacokinetics of Therapeutic Proteins

    … performed with two model drugs: filgrastim and denosumab. Their published structural pharmacokinetic models and model parameters were employed in the simulations of plasma concentration-time profiles at different IV and SC doses. The bioavailability was calculated as the ratio of dose-normalized …

    tenn-hsc Repository record for Challenges in the Pharmacokinetics of Therapeutic Proteins (opens in a new tab)

  2. Medication-Related osteonecrosis of the jaw in women with breast cancer. a literature review /

    … to bone metastases. Bisphosphonates (BPs) and Denosumab (DNB) are key bone-modifying agents (BMAs) used to target bone metabolism, reduce metastatic risk, and enhance adjuvant therapy efficacy in early-stage breast cancer. However, the usage of these agents carries risks, including adverse …

    vilnius Repository record for Medication-Related osteonecrosis of the jaw in women with breast cancer. a literature review / (opens in a new tab)

  3. Καταγματικός κίνδυνος σε ενηλίκους με κακοήθειες

    … φάρμακα όπως τα διφωσφονικά και denosumab. Συμπεράσματα Ο κίνδυνος κατάγματος σε ασθενείς με καρκίνο επηρεάζεται από διάφορους παρά¬γοντες, όπως ο τύπος του καρκίνου, το στάδιο της νόσου, οι αντικαρκινικές θεραπείες, η κατάσταση της υγείας των οστών και η παρουσία οστικών …

    athens Repository record for Καταγματικός κίνδυνος σε ενηλίκους με κακοήθειες (opens in a new tab)

  4. An assessment of the oral health status and dental treatment needs of oncology patients receiving bone modifying agents

    … and 6% (n=8) were planned for subcutaneous (SC) denosumab. 37 patients were current smokers (24.7%), and 23 patients were ex-smokers (15.3%). 65 patients (43.3%) did not have a general dental practitioner (GDP) at the time of presentation and 76 patients (50%) had a dental presenting complaint, …

    cork Repository record for An assessment of the oral health status and dental treatment needs of oncology patients receiving bone modifying agents (opens in a new tab)

  5. Targeting Cox-2 and Rank In Aggressive Breast Cancers: Inflammatory Breast Cancer and Triple-Negative Breast Cancer

    <p>Inflammatory breast cancer (IBC) and triple-negative breast cancer (TNBC) are two highly aggressive breast cancer subtypes associated with a poor outcome. Despite sensitivity to current treatment, these breast cancers subtypes have a high recurrence rate and proclivity to metastasize early. The …

    uthsc Repository record for Targeting Cox-2 and Rank In Aggressive Breast Cancers: Inflammatory Breast Cancer and Triple-Negative Breast Cancer (opens in a new tab)