Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"dendritic pathology"”.
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Neuronal Protection by a Novel C-terminal Hsp90 Modulator
… demonstrated significant protection against dendritic pathology and neuronal death in KU-32-treated vs vehicle-treated rTg4510 mice. Further studies were conducted to examine the potential mechanisms of drug action. We hypothesized that KU-32 activated the heat shock response leading to an …
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Investigation into the destructive and adaptive responses of neural cells to stress
… dyshomeostasis are often characterised by early dendritic pathology, I first studied dendritic vs. somatic responses of primary cortical neurons to these types of challenges in real-time. Using a wide range of genetically-encoded probes to measure Ca2+, ATP, NADH, glutathione and glutamate, I …