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Showing 1 to 20 of 47 for “"degradation product"”.
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Degradation Product Analysis of Bismaleimide Composite
… allows for the identification of decomposition products by evolved gas analysis. This combination of thermogravimetric analysis (TGA) and evolved gas analysis by FTIR and MS yields complementary information regarding pyrolysis and oxidative degradation products. Based on the TGA-FTIR-MS results, …
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Studies on Streptolidine, a Degradation Product of Streptothricin
Made available in DSpace on 2014-12-05T19:36:13Z (GMT). No. of bitstreams: 1 0013569.pdf: 5440251 bytes, checksum: 19821d5b07c831a81e368cb2a45a8eba (MD5) Previous issue date: 1955
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Design of a Validated Stability Indicating HPLC Method for the analysis of Patrin-2 (Lomeguatrib).
… cannot be stopped by neither MGMT nor MMR. The degradation behaviour of Patrin-2 was studied by subjecting it to various stress conditions. A validated stability indicating high-performance liquid chromatography method was established for the analysis of the drug in the presence of its various …
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Substandard antimicrobial drugs: detection methods and their contributions to antibiotic resistance
… to differentiate rifamycin drugs from the drug degradation product rifampicin quinone was developed by analyzing each drug’s unique interactions. While subinhibitory drug doses are known to select for antimicrobial resistance in vitro, the role of substandard anti-mycobacterial medicines in the …
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Cellulose-based amorphous solid dispersions enhance rifapentine delivery characteristics and dissolution kinetics in vitro
… treatment of tuberculosis, is reduced due to its degradation at gastric pH and low solubility at intestinal pH. We aimed to improve delivery properties in vitro by incorporating rifapentine into pH-responsive amorphous solid dispersions with cellulose derivatives including: …
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ATP, trehalose, glucose, and ammonium ion levels in the two cell types of Dictyostelium discoideum
… NH₄⁺ was interpreted as an indication of protein degradation, a source of energy in this organism. During the early stages of differentiation NH₄⁺ was localized only in stalk cells. However, it accumulated in spore cells during culmination such that levels were comparable in the two cell types by …
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Pesticide Adsorption and Degradation Properties as Influenced by Iron Oxidation State in Clay Minerals
… the adsorption and produced substantial degradation of all pesticides. When reacted with chemically treated clays, the total amount of atrazine removed from solution by the reduced clay was much greater than by the oxidized or reoxidized clays. Similar behavior was observed for the other …
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An Injectable Thermosensitive Hydrogel Potentially Used for Wound Dressing with Self-adhesive Properties
… water content, degradability, no cytotoxicity of degradation product to cells, and high in vivo biocompatibility. These hydrogels could also improve cell adhesion as well as promoting cell growth and proliferation. Moreover, the hydrogels could potentially present anti-bacterial properties when …
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Photolysis of fluorinated organic molecules: fluorine mass balances and the roles of nucleophiles, rings, and degree of fluorination
… are exposed to environmental conditions, abiotic degradation pathways such as photolysis may occur. Photolysis results from photon absorption by a chromophore on the molecule. Following photon absorption, chemical bond breakage, rearrangement, and product formation may occur. Indirect photolysis …
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An HPLC method for simultaneous determination of residual benomyl and MBC on apple foliage without cleanup
… and hexane (4:1) saturated with water. MBC, a degradation product of benomyl is identified if present as methyl l-(npropyl carbamoyl)-2-benzimidazole carbamate (MBC-n-PIC). Both benomyl and MBC-n-PIC can be detected with aKUltraviolet (UV) detector (280nm) at a concentration as low as 0.2 …
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A comparative study of certain soil-borne cereal pathogens with reference to carbohydrate utilisation and polysaccharide hydrolysis
… from culture medium did not prevent the production of pectin degrading enzymes by F. culmorum and C. sativus although its presence influenced early enzyme production. Low nitrate concentrations did not preclude cell wall polysaccharide degrading enzymes production. Multiple forms of …
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Tombusvirids Avoid and Exploit a Plant Exoribonuclease
… hypothesized that the svRNA represented a stable degradation product that could be functionally relevant to successful TNV-D infections. Through in vitro and in vivo analyses of TNV-D, I determined that the svRNA was indeed generated from incomplete digestion of the TNV-D genome by Xrn, and that …
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Dose-banding studies on oxaliplatin
… treatment and, through quality control and end-product testing, safeguards the infusion quality and patient safety. A range of studies were included in this thesis: an extended stability study on oxaliplatin infusions using a sequential temperature cycling design; studies on oxalate, a potential …
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Development of a Genetic Modification System in <i>Clostridium scatologenes</i> ATCC 25775 for Generation of Mutants
… is the model organism for the study of 3-MI production. 3-MI is an anaerobic degradation product of L-tryptophan and can cause pulmonary disorders and death in cattle and goats. To elucidate the 3-MI biosynthesis pathway and the underlying genes, it is necessary to develop a system to allow …
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Molecular candidates for Blocking the Transmission of Vector-Borne diseases
… analysis revealed reduced D-Dimer, a fibrin degradation product, in ticks fed on immunocompromised hosts. In addition, ticks fed on immunocompromised hosts exhibit a lower expression of the arthropod HSP70-like molecule that correlated with higher engorgement weights. This differential …
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Biochemical and Functional Characterization of Induced Terpene Formation in Arabidopsis Roots
… family that catalyzes a root-specific oxidative degradation of the C30-triterpene precursor arabidiol thereby causing the release of DMNT and a C19-degradation product named arabidonol. We found that DMNT shows inhibitory effects on P. irregulare mycelium growth and oospore germination in vitro, …
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The fate of organotin biocides in marine antifouling elastomers.
… elastomers demonstrate the extensive chemical degradation suffered by these compounds upon incorporation into the elastomer matrix.Spectroscopic and chromatographic analyses of a marine-exposed elastomer, originally containing bis(TBT)oxide (TBTO), revealed the presence of monobutyl- and …
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Preparation, Characterization and Toxicity Evaluation of a Novel Sustained Release Delivery System for a Hydrogen Sulfide Donor - GYY 4137
… of 4-methoxyphenylphosphonic acid (a GYY 4137 degradation product) in STF confirming the mechanism of H2S release. Benzyl benzoate and benzyl alcohol solvent blend exhibited toxicity in Y79 retinoblastoma cells which should be substituted with less toxic solvent in a future extension of this …
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